Evidence map›Paper›PMID 30518649›Full record

ArticleJournal of virology2019

The Need for Speed: Run-On Oligomer Filament Formation Provides Maximum Speed with Maximum Sequestration of Activity.

Claudia J Barahona, L Emilia Basantes, Kassidy J Tompkins, Desirae M Heitman, Barbara I Chukwu, Juan Sanchez, Jonathan L Sanchez, Niloofar Ghadirian, Chad K Park, N C Horton

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Novel insights into filament-forming enzymes.Nature reviews. Molecular cell biology · 2020
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Claudia J BarahonaDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
L Emilia BasantesDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Kassidy J TompkinsDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Desirae M HeitmanDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Barbara I ChukwuDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Juan SanchezDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Jonathan L SanchezDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Niloofar GhadirianDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Chad K ParkDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
N C HortonDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA nhorton@u.arizona.edu.
University of Arizona · US

Funding

GRADUATE TRAINING IN BIOCHEMISTRY AND MOLECULAR BIOLOGYT32GM008659 · NIGMS · UNIVERSITY OF ARIZONA · PI CAPALDI, ANDREW PAUL, WEINERT, TED A. · 1997 to 2019
$5.3M
Radiation and Fluorescence Imaging Technology for Biology and BiochemistryS10OD013237 · OD · UNIVERSITY OF ARIZONA · PI PARK, CHAD KING · 2013 to 2013
$137k
NIGMS NIH HHS T32 GM008659NIH HHS S10 OD013237
6 · The paper itself

Abstract

Here, we investigate an unusual antiviral mechanism developed in the bacterium

Indexed as

BacteriophagesBase SequenceDeoxyribonucleases, Type II Site-SpecificDNA, ViralEnzyme ActivationStreptomyces griseusStructure-Activity RelationshipSubstrate SpecificityDeoxyribonucleases, Type II Site-SpecificDNA, Viralendodeoxyribonuclease SgrAIantiphage mechanismenzyme kineticsenzyme mechanismfilament forming enzymeskinetic simulationsphage infectionprotein structure-functionrestriction endonuclease

Identifiers

PMID30518649
PMCPMC6384071
OpenAlexW2903021492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.