Evidence map›Paper›PMID 30518636›Full record

ArticleEMBO molecular medicine2019

Murine

Junning Yang, Claire Simonneau, Robert Kilker, Laura Oakley, Matthew D Byrne, Zuzana Nichtova, Ioana Stefanescu, Fnu Pardeep-Kumar, Sushil Tripathi, Eric Londin and 8 more

Open access · goldAbstract read
In one paragraph

Article in EMBO molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Endoscopic third ventriculostomy for diencephalosynapsis-related hydrocephalus in MPDZ gene syndrome: a case report and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Novel Insights into Emx2 and Dmrta2 Cooperation during Cortex Development and Evidence for Dmrta2 Function in the Choroid Plexus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Genes · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Loss of symmetric cell division of apical neural progenitors drivesmedRxiv : the preprint server for health sciences · 2024
    Article
  13. Genetic and molecular mechanisms of hydrocephalus.Frontiers in molecular neuroscience · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 4 countries.

Junning YangCardeza Center for Vascular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Claire SimonneauCardeza Center for Vascular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Robert KilkerCardeza Center for Vascular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Laura OakleyDepartment of Neuroscience, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Matthew D ByrneDepartment of Neuroscience, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Zuzana NichtovaDepartment of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Ioana StefanescuCardeza Center for Vascular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Fnu Pardeep-KumarDepartment of Radiology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Sushil TripathiDepartment of Radiology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Eric LondinComputational Medicine Center, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Pascale Saugier-VeberDepartment of Genetics, University of Rouen, Rouen, France.
Belinda WillardProteomics Core Facility, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Mathew ThakurDepartment of Radiology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Stephen PickupDepartment of Radiology, University of Pennsylvania Medical School, Philadelphia, PA, USA.
Hiroshi IshikawaLaboratory of Clinical Regenerative Medicine, Department of Neurosurgery, Faculty of Medicine University of Tsukuba, Tsukuba-City, Ibaraki, Japan.
Horst SchrotenPediatric Infectious Diseases, University Children's Hospital Mannheim, Heidelberg University, Mannheim, Germany.
Richard SmeyneDepartment of Neuroscience, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Arie HorowitzCardeza Center for Vascular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA arie.horowitz@jefferson.edu.ORCID 0000-0001-6239-1287
Thomas Jefferson University · USCleveland Clinic · USHeidelberg University · DEUniversité de Rouen Normandie · FRUniversity of Pennsylvania · USUniversity of Tsukuba · JP

Funding

X-Ray Crystallography and Macromolecular CharacterizationP30CA056036 · NCI · THOMAS JEFFERSON UNIVERSITY · PI Andrew Chapman · 1995 to 2026
$94.8M
Regulation of endothelial cell junctions by VEGF and angiopoietinR01HL119984 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI HOROWITZ, ARIE · 2014 to 2017
$1.6M
High-End Instrumentation (HEI) Grant Program (S10)S10OD023436 · OD · CLEVELAND CLINIC LERNER COM-CWRU · PI WILLARD, BELINDA BELLE · 2017 to 2017
$873k
PET for Molecular Imaging of Small AnimalsS10RR023709 · NCRR · THOMAS JEFFERSON UNIVERSITY · PI THAKUR, MATHEW LAXMAN · 2008 to 2008
$500k
SPECT/CT for Molecular Imaging Facility at TJUS10OD012406 · OD · THOMAS JEFFERSON UNIVERSITY · PI THAKUR, MATHEW LAXMAN · 2014 to 2014
$300k
NCI NIH HHS P30 CA056036NCRR NIH HHS S10 RR023709NHLBI NIH HHS R01 HL119984NIH HHS S10 OD012406NIH HHS S10 OD023436
6 · The paper itself

Abstract

Though congenital hydrocephalus is heritable, it has been linked only to eight genes, one of which is

Indexed as

Capillary PermeabilityAnimalsCarrier ProteinsChoroid PlexusContrast MediaDisease Models, AnimalEpithelial CellsHydrocephalusMagnetic Resonance ImagingMembrane ProteinsMiceCarrier ProteinsContrast MediaMembrane ProteinsMpdz protein, mousecerebrospinal fluidchoroid plexushydrocephalusmagnetic resonance imagingproteomics

Identifiers

PMID30518636
PMCPMC6328942
OpenAlexW2951886469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.