Evidence map›Paper›PMID 30518623›Full record

ArticleJournal of cell science2018

Bexarotene - a novel modulator of AURKA and the primary cilium in

Pratim Chowdhury, Reid T Powell, Clifford Stephan, Ivan P Uray, Tia Talley, Menuka Karki, Durga Nand Tripathi, Yong Sung Park, Michael A Mancini, Peter Davies and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Pratim ChowdhuryCenter for Precision Environmental Health, Baylor College of Medicine, Houston, TX 77030, USA.
Reid T PowellCenter for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, TX 77030, USA.
Clifford StephanCenter for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, TX 77030, USA.
Ivan P UrayDepartment of Clinical Oncology, University of Debrecen, Debrecen 4032, Hungary.
Tia TalleyCenter for Precision Environmental Health, Baylor College of Medicine, Houston, TX 77030, USA.
Menuka KarkiCenter for Precision Environmental Health, Baylor College of Medicine, Houston, TX 77030, USA.
Durga Nand TripathiCenter for Precision Environmental Health, Baylor College of Medicine, Houston, TX 77030, USA.
Yong Sung ParkCenter for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, TX 77030, USA.
Michael A ManciniCenter for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, TX 77030, USA.
Peter DaviesCenter for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M College of Medicine, Houston, TX 77030, USA.
Ruhee DereCenter for Precision Environmental Health, Baylor College of Medicine, Houston, TX 77030, USA ruhee.dere@bcm.edu.ORCID 0000-0002-1457-609X
Baylor College of Medicine · USUniversity of Debrecen · HU

Funding

Methyltransferase Contributions to Genomic Stability and CancerR01CA203012 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RATHMELL, WENDY KIMRYN, WALKER, CHERYL L. · 2016 to 2020
$2.2M
Sleep Disordered Breathing and Nocturnal Hypoxia in Non-small Cell Lung CancerR21CA125213 · NCI · EMORY UNIVERSITY · PI VENA, CATHERINE I · 2007 to 2008
$337k
NCI NIH HHS R01 CA203012NCI NIH HHS R21 CA125213
6 · The paper itself

Abstract

Loss of the gene von Hippel-Lindau (

Indexed as

Aurora Kinase ABexaroteneCarcinoma, Renal CellCell Line, TumorCiliaGene Expression Regulation, NeoplasticHumansMutationVon Hippel-Lindau Tumor Suppressor ProteinAURKA protein, humanAurora Kinase ABexaroteneVon Hippel-Lindau Tumor Suppressor ProteinAURKABexarotenePrimary ciliaPrimary HTS screenVHL

Identifiers

PMID30518623
PMCPMC6307881
OpenAlexW2903271123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.