Evidence map›Paper›PMID 30518599›Full record

Trial reportThe Journal of experimental medicine2019

A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets.

Marion Salou, François Legoux, Jules Gilet, Aurélie Darbois, Anastasia du Halgouet, Ruby Alonso, Wilfrid Richer, Anne-Gaëlle Goubet, Céline Daviaud, Laurie Menger and 3 more

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 198 citations in OpenAlex.

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  13. Metabolic control of innate-like T cells.Nature reviews. Immunology · 2026
    Review
  14. Article
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  17. Liver transplant-facilitated CD161Nature communications · 2025
    Article
  18. Review
  19. Article
  20. Article

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Marion SalouInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.
François LegouxInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.
Jules GiletInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.
Aurélie DarboisInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.
Anastasia du HalgouetInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.
Ruby AlonsoInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.
Wilfrid RicherInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.ORCID 0000-0002-4739-5025
Anne-Gaëlle GoubetInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.
Céline DaviaudAnimal Facility, Institut Curie, Paris, France.
Laurie MengerInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.
Emanuele ProcopioInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.
Virginie PremelInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France.
Olivier LantzInstitut National de la Santé et de la Recherche Médicale U932, PSL University, Institut Curie, Paris, France olivier.lantz@curie.fr.ORCID 0000-0003-3161-7719
Inserm · FRInstitut Curie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosal-associated invariant T (MAIT) cells are abundant T cells with unique specificity for microbial metabolites. MAIT conservation along evolution indicates important functions, but their low frequency in mice has hampered their detailed characterization. Here, we performed the first transcriptomic analysis of murine MAIT cells. MAIT1 (RORγt

Indexed as

AnimalsFemaleHumansIntercellular Adhesion Molecule-1LiverLungLymphocyte Function-Associated Antigen-1MaleMiceMice, TransgenicNatural Killer T-CellsOrgan SpecificitySpleenThymus GlandTranscriptomeICAM1 protein, humanIcam1 protein, mouseIntercellular Adhesion Molecule-1Lymphocyte Function-Associated Antigen-1

Identifiers

PMID30518599
PMCPMC6314520
OpenAlexW2902836950

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.