ArticleBMJ open2018
Cohort profile: the Buffalo OsteoPerio microbiome prospective cohort study.
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 24 citations in OpenAlex.
- Periodontal inflamed surface area (PISA) system and components: Potential for exploring the periodontal systemic interface.Journal of periodontology · 2026Article
- The Silent Shift of Menopause: The Intersection between Salivary Glands, Oral Cavity Status, and Cardiovascular Health.Arquivos brasileiros de cardiologia · 2026Review
- Comparison of Bacterial Adhesion on Two Different Suture Materials After Tooth Extraction in Women Receiving Antiresorptive Therapy: An Exploratory Clinical Study with Prospective Data Collection.Journal of clinical medicine · 2026Article
- Periodontal Disease and Osteoporosis: A Bidirectional Relationship.Advances in experimental medicine and biology · 2026Review
- Proton Pump Inhibitors and Biomarkers of Haemostasis in Postmenopausal Women: The Buffalo OsteoPerio Study.Basic & clinical pharmacology & toxicology · 2026Article
- Oral microbiome, periodontal disease and systemic bone-related diseases in the era of homeostatic medicine.Journal of advanced research · 2025Review
- Outer membrane vesicles of Porphyromonas gingivalis impede bone regeneration by inducing ferroptosis via the Hippo-YAP signaling pathway.Journal of nanobiotechnology · 2025Article
- Association Between Healthy Eating Index-2020 and Oral Microbiome Among Postmenopausal Women.The Journal of nutrition · 2025Article
- Visceral adiposity in postmenopausal women is associated with a pro-inflammatory gut microbiome and immunogenic metabolic endotoxemia.Microbiome · 2024Article
- Accuracy of self-reported treated hypertension in the women's health initiative: Comparisons with medication inventories.Journal of clinical hypertension (Greenwich, Conn.) · 2024Observational
- Association between dietary patterns and periodontal disease: The OsteoPerio cohort study.Journal of clinical periodontology · 2024Article
- Defining Porphyromonas gingivalis strains associated with periodontal disease.Scientific reports · 2024Article
- Alcohol Consumption and the Diversity of the Oral Microbiome in Postmenopausal Women.The Journal of nutrition · 2024Article
- Relationship between the subgingival microbiome and menopausal hormone therapy use: The Buffalo OsteoPerio study.Journal of periodontology · 2022Article
- Oral Microbiome Is Associated With Incident Hypertension Among Postmenopausal Women.Journal of the American Heart Association · 2022Article
- Dietary carbohydrate intake is associated with the subgingival plaque oral microbiome abundance and diversity in a cohort of postmenopausal women.Scientific reports · 2022Article
- Subgingival microbiome is associated with alveolar bone loss measured 5 years later in postmenopausal women.Journal of periodontology · 2021Article
- Could Vitamin D influence risk for Periodontal Disease - to "D" or not to "D"?Current oral health reports · 2020Article
- The Buffalo OsteoPerio Studies: Summary of our findings and the unique contributions of Robert J. Genco, DDS, PhD.Current oral health reports · 2020Article
- The Subgingival Microbiome Relationship to Periodontal Disease in Older Women.Journal of dental research · 2019Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe Buffalo Osteoporosis and Periodontal Disease (OsteoPerio) study is a prospective cohort study focused on the relationship between the microbiome and oral and systemic health outcomes in postmenopausal women. The cohort was established to examine how the oral microbiome is affected by (and how it affects) periodontal disease presence, severity and progression and to characterise the relationship between the microbiome, lifestyle habits and systemic disease outcomes.
participantsParticipants (n=1342) were postmenopausal women who were participating in the Women's Health Initiative observational study at the Buffalo, New York clinical centre. There were 1026 participants at the 5-year follow-up visit and 518 at the 15-year visit. FINDINGS TO DATE: Data collected include questionnaires, anthropometric measures, serum blood and saliva samples. At each clinic visit, participants completed a comprehensive oral examination to measure oral health and the oral microbiome. Preliminary findings have contributed to our understanding of risk factors for periodontal disease and the relationship between the oral microbiome and periodontal disease. FUTURE PLANS: The novel microbiome data collected on a large sample of participants at three time points will be used to answer a variety of research questions focused on temporal changes in the microbiome and the relationship between the oral microbiome and oral and systemic disease outcomes. Little is currently known about the relationship between the oral microbiome and health outcomes in older adults; data from the OsteoPerio cohort will fill this gap. Microbiome samples are currently being analysed using next-generation sequencing technology with an anticipated completion date of late 2018.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.