Evidence map›Paper›PMID 30518571›Full record

ReviewClinical science (London, England : 1979)2018

Investigating the RAS can be a fishy business: interdisciplinary opportunities using Zebrafish.

Scott Hoffmann, Linda Mullins, Charlotte Buckley, Sebastien Rider, John Mullins

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical science (London, England : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Renin Cells, the Kidney, and Hypertension.Circulation research · 2021
    Review
  4. Article
  5. Review
  6. Ontogeny of renin gene expression in the chicken, Gallus gallus.General and comparative endocrinology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Scott HoffmannUniversity of Edinburgh/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, The University of Edinburgh, 47, Little France Crescent, Edinburgh EH16 4TJ, U.K.
Linda MullinsUniversity of Edinburgh/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, The University of Edinburgh, 47, Little France Crescent, Edinburgh EH16 4TJ, U.K.
Charlotte BuckleyUniversity of Edinburgh/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, The University of Edinburgh, 47, Little France Crescent, Edinburgh EH16 4TJ, U.K.
Sebastien RiderUniversity of Edinburgh/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, The University of Edinburgh, 47, Little France Crescent, Edinburgh EH16 4TJ, U.K.
John MullinsUniversity of Edinburgh/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, The University of Edinburgh, 47, Little France Crescent, Edinburgh EH16 4TJ, U.K. j.mullins@ed.ac.uk.
The Queen's Medical Research Institute · GB

Funding

British Heart Foundation RE/13/3/30183Medical Research Council MR/K015710/1
6 · The paper itself

Abstract

The renin-angiotensin system (RAS) is highly conserved, and components of the RAS are present in all vertebrates to some degree. Although the RAS has been studied since the discovery of renin, its biological role continues to broaden with the identification and characterization of new peptides. The evolutionarily distant zebrafish is a remarkable model for studying the kidney due to its genetic tractability and accessibility for

Indexed as

Renin-Angiotensin SystemAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAnimalsAnimals, Genetically ModifiedGene Expression Regulation, DevelopmentalKidney DiseasesLuminescent ProteinsPronephrosSignal TransductionZebrafishZebrafish ProteinsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsLuminescent ProteinsZebrafish ProteinsoptogeneticsReninSPIMtransgenicsZebrafish

Identifiers

PMID30518571
PMCPMC6279434
OpenAlexW2902255890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.