Observational studyJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018
Varying Hypopnea Definitions Affect Obstructive Sleep Apnea Severity Classification and Association With Cardiovascular Disease.
Observational study in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- Wireless wearable sensors can facilitate rapid detection of sleep apnea in hospitalized stroke patients.Sleep · 2024Trial
- Trial
- The Pathophysiological Association Between Obstructive Sleep Apnea and Glaucoma: A Current Update.Journal of clinical medicine · 2026Review
- Impact of Hypopnoea Classifications on the Assessment of Sleep Disordered Breathing in Heart Failure.Cardiac failure review · 2025Review
- Achieving Better Understanding of Obstructive Sleep Apnea Treatment Effects on Cardiovascular Disease Outcomes through Machine Learning Approaches: A Narrative Review.Journal of clinical medicine · 2024Review
- Association of obstructive sleep apnea with cardiometabolic diseases and cardiovascular mortality.The clinical respiratory journal · 2023Article
- Coupling analysis of heart rate variability and cortical arousal using a deep learning algorithm.PloS one · 2023Article
- Quality measures for the care of adult patients with obstructive sleep apnea: 2022 update after measure maintenance.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- A transition to the American Academy of Sleep Medicine-recommended hypopnea definition in adults: initiatives of the Hypopnea Scoring Rule Task Force.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Observational
- Association between obstructive sleep apnea and multiple involuntary job loss history among recently unemployed adults.Sleep health · 2021Article
- What are we missing? Hypertension and hypopneas.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Incidence of hypertension in obstructive sleep apnea using hypopneas defined by 3 percent oxygen desaturation or arousal but not by only 4 percent oxygen desaturation.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Risk factors and fraction of exhaled nitric oxide in obstructive sleep apnea in adults.The Journal of international medical research · 2020Article
- Longitudinal effect of nocturnal R-R intervals changes on cardiovascular outcome in a community-based cohort.BMJ open · 2019Article
- Respiratory Mandibular Movement Signals Reliably Identify Obstructive Hypopnea Events During Sleep.Frontiers in neurology · 2019Article
- The (Still) Elusive Definition of Hypopnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018Article
- Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
STUDY
objectivesTo compare clinical features and cardiovascular risks in patients with obstructive sleep apnea (OSA) based on ≥ 3% desaturation or arousal, and ≥ 4% desaturation hypopnea criteria.
methodsThis is a cross-sectional analysis of 1,400 veterans who underwent polysomnography for suspected sleep-disordered breathing. Hypopneas were scored using ≥ 4% desaturation criteria per the American Academy of Sleep Medicine (AASM) 2007 guidelines, then re-scored using ≥ 3% desaturation or arousal criteria per AASM 2012 guidelines. The effect on OSA disease categorization by these two different definitions were compared and correlated with symptoms and cardiovascular associations using unadjusted and adjusted logistic regression.
resultsThe application of the ≥ 3% desaturation or arousal definition of hypopnea captured an additional 175 OSA diagnoses (12.5%). This newly diagnosed OSA group (OSA
conclusionsThe most current AASM criteria for hypopnea identify a unique group of patients who are sleepy, but who are not at increased risk for cardiovascular disease. Though the different hypopnea definitions result in recategorization of OSA severity, severe disease whether defined by ≥ 3% desaturation/arousals or ≥ 4% desaturation remains predictive of cardiac arrhythmias. COMMENTARY: A commentary on this article appears in this issue on page 1971.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.