ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2018
Long Sleep Duration, Insomnia, and Insomnia With Short Objective Sleep Duration Are Independently Associated With Short Telomere Length.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Insomnia nosology: a systematic review and critical appraisal of historical diagnostic categories and current phenotypes.Journal of sleep research · 2023Pooled it
- Mechanisms Linking Insomnia and Cardiometabolic Disease Risk.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Comparative analysis of telomere length in peripheral blood of breast cancer BRCA1 mutation carriers and non-carriers.Discover oncology · 2026Article
- Sleep Disruption and Shift Work Associate with Increased Risk of Reproductive Endocrine Disorders: Evidence from UK Biobank and Mendelian Randomization.International journal of women's health · 2026Article
- Exploring Chronic Pain, Immune Dysfunction and Lifestyle: A Focus on T Cell Exhaustion and Senescence.Biomolecules · 2025Review
- Association of Hypertension With Telomere Length, Considering Non-Genetic and Genetic Factors, in Middle-Aged Koreans.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Article
- Insomnia Phenotypes, Cardiovascular Risk and Their Link to Brain Health.Circulation research · 2025Review
- Sleep Duration Polygenic Risk and Phenotype: Associations with Biomarkers of Accelerated Aging in the Baltimore Longitudinal Study of Aging.International journal of aging & human development · 2025Article
- Association of self-reported sleep duration with leukocyte telomere length in type 2 diabetes mellitus patients.Frontiers in endocrinology · 2025Article
- Quercetin Intake and Absolute Telomere Length in Patients with Type 2 Diabetes Mellitus: Novel Findings from a Randomized Controlled Before-and-After Study.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Associations of measured and genetically predicted leukocyte telomere length with vascular phenotypes: a population-based study.GeroScience · 2024Article
- Association between modifiable lifestyle factors and telomere length: a univariable and multivariable Mendelian randomization study.Journal of translational medicine · 2024Article
- The need to promote sleep health in public health agendas across the globe.The Lancet. Public health · 2023Review
- The Pendulum Swings Both Ways: Evidence for U-Shaped Association between Sleep Duration and Mental Health Outcomes.International journal of environmental research and public health · 2023Article
- Insomnia with objective short sleep duration in community-living older persons: A multifactorial geriatric health condition.Journal of the American Geriatrics Society · 2023Article
- The association between sleep quality and telomere length: A systematic literature review.Brain, behavior, & immunity - health · 2023Review
- The impact of insomnia on frailty and the hallmarks of aging.Aging clinical and experimental research · 2023Review
- Associations between shortened telomeres and rheumatoid arthritis-associated interstitial lung disease among U.S. Veterans.Respiratory medicine · 2022Article
- Changes in telomere length and serum neurofilament light chain levels in female patients with chronic insomnia disorder.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesWe aimed to determine the association between short telomere length, sleep parameters, and sleep disorders in an adult general population sample.
methodsAs part of the EPISONO cohort (São Paulo, Brazil), 925 individuals answered questionnaires, underwent a full-night polysomnography and clinical assessment, and had peripheral blood collected for DNA extraction. Insomnia was diagnosed based on the Diagnostic and Statistical Manual of Mental Disorders, 4th edition; and obstructive sleep apnea was defined according to apnea-hypopnea index. For the objective insomnia phenotype, we combined insomnia diagnosis with total sleep time from polysomnography with a cutoff of 360 minutes, allowing the classification of six groups. Self-reported sleep duration was used to classify the individuals as short (< 6 hours), average (6 to 8 hours) and long (> 8 hours) sleepers. The leukocyte telomere length was measured using quantitative real-time polymerase chain reaction. Based on its distribution, we considered leukocyte telomere length < 10th percentile as short telomere and leukocyte telomere length ≥ 10th percentile as non-short telomere.
resultsAfter adjusting for sex, age, and body mass index, only insomnia disorder (odds ratio [OR] = 2.654, 95% confidence interval [CI] = 1.025-6.873,
conclusionsOur findings support the existence of an association among insomnia, insomnia phenotype, and self-reported long sleep duration with the maintenance of telomere length. COMMENTARY: A commentary on this article appears in this issue on page 1975.
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