ArticleRadiation oncology (London, England)2018
Performance of gimbal-based dynamic tumor tracking for treating liver carcinoma.
Article in Radiation oncology (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 13 citations in OpenAlex.
- Article
- Megavoltage intrafraction monitoring and position uncertainty in gimbaled markerless dynamic tumor tracking treatment of lung tumors.Medical physics · 2025Article
- End-to-end testing for stereotactic radiotherapy including the development of a Multi-Modality phantom.Zeitschrift fur medizinische Physik · 2024Article
- Markerless dynamic tumor tracking (MDTT) radiotherapy using diaphragm as a surrogate for liver targets.Journal of applied clinical medical physics · 2024Article
- Offline generator for digitally reconstructed radiographs of a commercial stereoscopic radiotherapy image-guidance system.Journal of applied clinical medical physics · 2022Article
- Technical Note: Comprehensive performance tests of the first clinical real-time motion tracking and compensation system using MLC and jaws.Medical physics · 2020Article
- Technological quality requirements for stereotactic radiotherapy : Expert review group consensus from the DGMP Working Group for Physics and Technology in Stereotactic Radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020Review
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5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundSince the introduction of tumor tracking in radiotherapy, it is possible to ensure a precise irradiation of moving targets. To follow the tumor movement, most systems rely on the detection of implanted markers and correlation models between the internal and external patient movement. This study reports the clinical workflow and first results of the dynamic tumor tracking (DTT) performance for patients with liver carcinoma at the Vero SBRT system of the University Hospital Erlangen regarding the detection of the internal marker and the changes of the determined correlation models.
methodsSo far 13 liver patients were treated with DTT. For each patient, two fiducial markers (FM), which are monitored with X-rays during treatment, were implanted in the vicinity of the tumor. All patients received a fraction dose of 4-6 Gy with 8 to 12 fractions. Treatment and patient data is evaluated by processing the acquired log-files of the DTT treatment. Based on this, the marker detection and the changes of the correlation model between the internal and external movement is investigated.
resultsThe median treatment time was 19:42 min. During treatment a median of 173 X-ray stereoscopic images were acquired. The marker detection was successful in 64.6% of the images. The FM detection is independent of the relative angle between the marker and the imager, but shows a dependency on the average intensity surrounding the FM position within the kV images. The number of correlation models needed during treatment increases in the presence of baseline shifts. The comparison of the correlation models shows large differences in the internal-external correlation between the different models acquired for one patient.
conclusionThirteen liver patients were treated with DTT at the Vero SBRT system and the marker detection was analyzed. Furthermore, the importance of regularly monitoring the internal target motion could be shown, since the correlation between the internal and external motion changes considerably over the course of the treatment.
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