ArticleCardiovascular diabetology2018
Cognitive function in adolescence and the risk for premature diabetes and cardiovascular mortality in adulthood.
Article in Cardiovascular diabetology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Cardiovascular morbidity, diabetes and cancer risk among children and adolescents with severe obesity.Cardiovascular diabetology · 2020Pooled it
- Polyendocrine Metabolic Ovarian Syndrome and the Entire Spectrum of Gestational Dysglycemia: A Population-Based Cohort Study.Diabetes, obesity & metabolism · 2026Article
- Adolescent intelligence and imaging-detected atherosclerosis in middle age: a population study of Swedish men.BMC medicine · 2026Article
- Thyroid, Celiac, and Other Autoimmune Diseases and the Risk of Incident Type 1 Diabetes in Young Adulthood.Diabetes care · 2026Article
- Cognitive function in childhood and cardiovascular disease risk factors up to 6 decades later: Pooled data from two birth cohort studies.medRxiv : the preprint server for health sciences · 2026Article
- Article
- Adolescent to adulthood weight trajectories and the risk of obesity-related cancers, overall and early-onset: a population-based cohort study.EClinicalMedicine · 2026Article
- Adolescent cognitive function and risk of gestational diabetes mellitus: A retrospective population-based cohort study.PloS one · 2026Article
- Adolescent Intelligence and Imaging-Based Atherosclerosis in middle age: A Population Study of Swedish Men.medRxiv : the preprint server for health sciences · 2025Article
- Multilevel multiverse meta-analysis indicates lower IQ as a risk factor for physical and mental illness.Communications psychology · 2025Article
- Article
- Heritability of Body Mass Index Among Familial Generations.JAMA network open · 2024Article
- Review
- Neuropsychological Aspects of Children's Somatic Disorders in Chronic Diseases: Diabetes and Short Stature in the Developmental Period.Biomedicines · 2023Article
- Associations of Adolescence Exposure to Industrial Air Pollution with Cancer in Young Adults.Environment & health (Washington, D.C.) · 2023Article
- Anticholinergic burden in middle and older age is associated with lower cognitive function, but not with brain atrophy.British journal of clinical pharmacology · 2023Article
- High intelligence is not associated with a greater propensity for mental health disorders.European psychiatry : the journal of the Association of European Psychiatrists · 2022Article
- Transcriptome-wide and stratified genomic structural equation modeling identify neurobiological pathways shared across diverse cognitive traits.Nature communications · 2022Article
- Obesity in late adolescence and incident type 1 diabetes in young adulthood.Diabetologia · 2022Article
- Correlation of physical and cognitive impairment in diabetic and hypertensive frail older adults.Cardiovascular diabetology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpidemiological studies have demonstrated a relationship between cognitive function in youth and the future risk of death. Less is known regarding the relationship with diabetes related death. This study assessed the relationship between cognitive function in late adolescence and the risk for diabetes, cardiovascular- (CVD) and all-cause mortality in adulthood.
methodsThis retrospective study linked data from 2,277,188 16-19 year olds who had general intelligence tests (GIT) conducted during pre-military recruitment assessment with cause of death as coded by the Israel Central Bureau of Statistics. The associations between cognitive function and cause-specific mortality were assessed using Cox models.
resultsThere were 31,268 deaths that were recorded during 41,916,603 person-years of follow-up, with a median follow-up of 19.2 (IQR 10.7, 29.5) years. 3068, 1443, 514 and 457 deaths were attributed to CVD, CHD, stroke, and diabetes, respectively. Individuals in the lowest GIT vs. highest GIT quintiles in unadjusted models had the highest risk for all-cause mortality (HR 1.84, 95% CI 1.78, 1.91), total CVD (HR 3.32, 95% CI 2.93, 3.75), CHD (HR 3.49 95% CI 2.92, 4.18), stroke (HR 3.96 95% CI 2.85, 5.5) and diabetes-related (HR 6.96 95% CI 4.68, 10.36) mortality. These HRs were attenuated following adjustment for age, sex, birth year, body-mass index, residential socioeconomic status, education and country of origin for all-cause (HR 1.23, 95% CI 1.17, 1.28), CVD (HR 1.76, 95% CI 1.52, 2.04), CHD (HR 1.7 95% CI 1.37, 2.11), stroke (HR 2.03, 95% CI 1.39, 2.98) and diabetes-related (HR 3.14 95% CI 2.00, 4.94) mortality. Results persisted in a sensitivity analyses limited to participants with unimpaired health at baseline and that accounted competing risk.
conclusionsThis analysis of over 2 million demonstrates a strong relationship between cognitive function at youth and the risk for diabetes, all-cause and CVD-related mortality independent of adolescent obesity.
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