Evidence map›Paper›PMID 30518351›Full record

ArticleBMC psychiatry2018

Mechanisms associated with maternal adverse childhood experiences on offspring's mental health in Nairobi informal settlements: a mediational model testing approach.

Manasi Kumar, Beatrice Amugune, Beatrice Madeghe, Grace Nduku Wambua, Judith Osok, Anastasia Polkonikova-Wamoto, David Bukusi, Fred Were, Keng-Yen Huang

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Manasi KumarDepartment of Psychiatry, University of Nairobi, Nairobi, Kenya. m.kumar@ucl.ac.uk.ORCID 0000-0002-9773-8014
Beatrice AmuguneDepartment of Pharmacy, University of Nairobi, Nairobi, Kenya.
Beatrice MadegheDepartment of Food and Nutrition Sciences, University of Nairobi, Nairobi, Kenya.
Grace Nduku WambuaDepartment of Clinical, Neuro- & Developmental Psychology, Vrije University of Amsterdam, Amsterdam, Netherlands.
Judith OsokDepartment of Psychiatry, University of Nairobi, Nairobi, Kenya.
Anastasia Polkonikova-WamotoDepartment of Psychiatry, University of Nairobi, Nairobi, Kenya.
David BukusiHead VCT and HIV Care, Kenyatta National Hospital, Nairobi, Kenya.
Fred WereCollege of Health Sciences, University of Nairobi, Nairobi, Kenya.
Keng-Yen HuangDepartment of Population Health, New York University School of Medicine, New York, USA.
University of Nairobi · KEKenyatta National Hospital · KENew York University · USVrije Universiteit Amsterdam · NL

Funding

Scaling up a family strengthening EBP to reduce child disruptive behavior problems in SSAU19MH110001 · NIMH · WASHINGTON UNIVERSITY · PI MCKAY, MARY MCKERNAN · 2016 to 2020
$3.9M
Mapping impact and developing mitigation strategies for climate change-mental health nexus in the context of vulnerable adolescent populations in KenyaK43TW010716 · FIC · UNIVERSITY OF NAIROBI · PI KUMAR, MANASI · 2018 to 2022
$648k
FIC NIH HHS K43 TW010716NIMH NIH HHS U19 MH110001
6 · The paper itself

Abstract

backgroundAdverse childhood experiences (ACEs) is a significant public health and social welfare problem in low-and middle income countries (LMICs). However, most ACEs research is based on developed countries, and little is known about mechanisms of early ACEs on adulthood health and offspring's wellbeing for populations in LMICs. This area is needed to guide social welfare policy and intervention service planning. This study addresses these research gaps by examining patterns of ACEs and understanding the role of ACEs on adulthood health (i.e., physical, mental health, experience of underage pregnancy) and offspring's mental health in Kenya. The study was guided by an Integrated Family Stress and Adverse Childhood Experiences Mediation Framework.

methodsThree hundred ninety four mothers from two informal communities in Kariobangi and Kangemi in Nairobi were included in this study. The Adverse Childhood Experiences International Questionnaire (ACE-IQ), the Kessler Psychological Distress Scale (K10), Overall Health and Quality of Life items, and Child Behavior Checklist were used to study research questions. Data was gathered through a one-time interview with mothers. Structural Equational Modeling (SEM) was applied for mediational mechanism testing.

resultsAmong 13 ACE areas, most mothers experienced multiple adversity during their childhood (Mean (SD) = 4.93 (2.52)), with household member treated violently (75%) as the most common ACE. SEM results showedthat all domains of ACEs were associated with some aspects of maternal health, and all three domains of maternal health (maternal mental health, physical health, and adolescent pregnancy) were significantly associated with development of offspring's mental health problems.

conclusionACEs are highly prevalent in Kenyan informal settlements. Consistent with cross cultural literature on family stress model, maternal ACEs are robust predictors for poor child mental health. Preventive interventions for child mental health need to address maternal adverse childhood traumatic experiences as well as their current health in order to effectively promote child mental health.

Indexed as

Adult ChildrenAdverse Childhood ExperiencesMothersQuality of LifeAdultChildFamily HealthFemaleHealth PlanningHumansKenyaMaleMental HealthMental Health ServicesNeeds AssessmentPrevalenceAdverse childhood experiencesExternalizing problemsFamily stress modelInternalizing problemsMaternal mental healthUrban poverty

Identifiers

PMID30518351
PMCPMC6280351
OpenAlexW2902488089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.