Evidence map›Paper›PMID 30518343›Full record

ArticleBMC gastroenterology2018

Risk factor for steatorrhea in pediatric chronic pancreatitis patients.

Lu Hao, Teng Wang, Lin He, Ya-Wei Bi, Di Zhang, Xiang-Peng Zeng, Lei Xin, Jun Pan, Dan Wang, Jun-Tao Ji and 12 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06946108 (Investigation on the Current Situation and Risk Factors Analysis of Exocrine Insufficiency in Chronic Pancreatitis), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06946108 completednot on this mapstarted 2022, after this paper: background citation

Investigation on the Current Situation and Risk Factors Analysis of Exocrine Insufficiency in Chronic Pancreatitis: A Prospective Cohort Investigation Study

Typeobservational_patient_registrySponsorChanghai HospitalRan2022 to 2024Enrolled1,101ConditionsChronic Pancreatitis, Pancreatic Exocrine InsufficiencyArmsDetection of Pancreatic Exocrine Function in Patients with Chronic Pancreatitis (CP)
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 1 country.

Lu HaoDepartment of Gastroenterology, Hainan Branch of Chinese PLA General Hospital, Hainan, China.
Teng WangDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Lin HeDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Ya-Wei BiDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Di ZhangDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Xiang-Peng ZengDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Lei XinDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Jun PanDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Dan WangDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Jun-Tao JiDepartment of Gastroenterology, Changhai Hospital, The Second Military Medical University, Shanghai, China.
Ting-Ting DuDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Jin-Huan LinDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Li-Sheng WangDepartment of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Guangdong, China.
Wen-Bin ZouDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Hui ChenDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Ting XieDepartment of Gastroenterology, Zhongda Hospital, Southeast University, Nanjing, China.
Hong-Lei GuoDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Bai-Rong LiDepartment of Gastroenterology, Air Force General Hospital, Beijing, China.
Zhuan LiaoDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China.
Zheng-Lei XuDepartment of Gastroenterology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Guangdong, China. 78249073@qq.com.
Zhao-Shen LiDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China. zhaoshen-li@hotmail.com.ORCID http://orcid.org/0000-0002-1650-4014
Liang-Hao HuDepartment of Gastroenterology, Gongli Hospital, The Second Military Medical University, Shanghai, China. lianghao-hu@hotmail.com.
Second Military Medical University · CNJinan University · CNAir Force General Hospital PLA · CNZhongda Hospital Southeast University · CN

Funding

National Natural Science Foundation of China 81470883National Natural Science Foundation of China 81500490National Natural Science Foundation of China 81770632National Natural Science Foundation of China 81770635Shanghai Outstanding Youth Doctor Training Program AB83030002015034Shanghai Rising-Star Program 17QA1405500Shanghai Youth Top-notch Talent Program HZW2016FZ67Three engineering training funds in Shenzhen SYJY201713
6 · The paper itself

Abstract

backgroundPediatric patients always suffer from chronic pancreatitis (CP), especially those with steatorrhea. This study aimed to identify the incidence of and risk factors for steatorrhea in pediatric CP. To our best knowledge, there is no pediatric study to document the natural history of steatorrhea in CP.

methodsCP patients admitted to our center from January 2000 to December 2013 were enrolled. Patients were assigned to the pediatric (< 18 years old) and adult group according to their age at onset of CP. Cumulative rates of steatorrhea in both groups were calculated. Risk factors for both groups were identified, respectively.

resultsThe median follow-up duration for the whole cohort was 7.6 years. In a total of 2153 patients, 13.5% of them were pediatrics. The mean age at the onset and the diagnosis of CP in pediatrics were 11.622 and 19.727, respectively. Steatorrhea was detected in 46 patients (46/291, 15.8%) in the pediatric group and in 447 patients (447/1862, 24.0%) in the adult group. Age at the onset of CP (hazard ratio [HR], 1.121), diabetes mellitus (DM, HR, 51.140), and severe acute pancreatitis (SAP, HR, 13.946) was identified risk factor for steatorrhea in the pediatric group.

conclusionsAge at the onset of CP, DM and SAP were identified risk factors for the development of steatorrhea in pediatric CP patients. The high-risk populations were suggested to be followed up closely. They may benefit from a full adequate pancreatic exocrine replacement therapy.

Indexed as

AdolescentAdultAge of OnsetChildDiabetes ComplicationsFemaleFollow-Up StudiesHumansMaleMiddle AgedPancreatitis, ChronicRisk FactorsSeverity of Illness IndexSteatorrheaChronic pancreatitisPediatricRisk factorsSteatorrhea

Identifiers

PMID30518343
PMCPMC6280450
OpenAlexW2903240958

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.