Evidence map›Paper›PMID 30518333›Full record

ArticleBMC infectious diseases2018

Assessment of HIV prevalence among MSM in Tokyo using self-collected dried blood spots delivered through the postal service.

Misao Takano, Kohta Iwahashi, Ikuo Satoh, Junko Araki, Takuya Kinami, Yuzuru Ikushima, Toshiya Fukuhara, Hiroo Obinata, Yasuyo Nakayama, Yoshimi Kikuchi and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Misao TakanoMedical Genomic Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan. mtakano@acc.ncgm.gp.jp.ORCID http://orcid.org/0000-0001-5059-110X
Kohta IwahashiAKTA, 2-15-13-302 Shinjuku, Shinjuku-ku, Tokyo, 160-0022, Japan.
Ikuo SatohPLACE TOKYO, 4-11-5-403 Takadanobaba, Shinjuku-ku, Tokyo, 169-0075, Japan.
Junko ArakiAKTA, 2-15-13-302 Shinjuku, Shinjuku-ku, Tokyo, 160-0022, Japan.
Takuya KinamiAKTA, 2-15-13-302 Shinjuku, Shinjuku-ku, Tokyo, 160-0022, Japan.
Yuzuru IkushimaPLACE TOKYO, 4-11-5-403 Takadanobaba, Shinjuku-ku, Tokyo, 169-0075, Japan.
Toshiya FukuharaPLACE TOKYO, 4-11-5-403 Takadanobaba, Shinjuku-ku, Tokyo, 169-0075, Japan.
Hiroo ObinataHigashi-Shinjuku Kokorono Clinic, 2F 6-28-12 Shinjuku, Shinjuku-ku, Tokyo, 160-0022, Japan.
Yasuyo NakayamaHigashi-Shinjuku Kokorono Clinic, 2F 6-28-12 Shinjuku, Shinjuku-ku, Tokyo, 160-0022, Japan.
Yoshimi KikuchiAIDS Clinical Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.
Shinichi OkaAIDS Clinical Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.
HIV Check Study Group
National Center for Global Health and Medicine · JPAkita Industrial Technology Center · JP

Funding

Grant for National Center for Global Health and Medicine 26-A-122
6 · The paper itself

Abstract

backgroundMen who have sex with men (MSM) are at high risk of HIV infection. However, there are only few data on HIV prevalence in MSM in Japan. The objective of this study was to explore the HIV prevalence in MSM at Shinjuku 2-chome, a well known gay quarter in Tokyo.

methodsMSM directly collected the dried blood spot (DBS) self-collection HIV test kit from a drop-in center in Shinjuku 2-chome between August 2015 and December 2016. The participants collected their own blood by finger-prick and anonymously posted the kit to the laboratory. The participants accessed the study website and checked the results of their tests using unique ID and password. DBS was soaked in phosphate buffered saline overnight and the eluted sample was examined by the fourth generation HIV Ag/Ab test of LUMIPULSE (FUJIREBIO INC.), and followed by HISCL (Sysmex Corp.) when the first assay was positive. The result was defined provisionally positive if both were positive.

resultsA total of 1702 HIV test kits were distributed and 1403 DBS were returned (return rate: 82.4%). Since 20.2% of participants collected the test kit more than once, the estimated number of actual test kit users was 1120. Based on the results of the test kit, 34 cases were provisionally diagnosed with HIV. The estimated prevalence was 3.04% (95% confidence interval: 2.03-4.04). Of these 34, 24 (70.6%) were later confirmed to be HIV-positive in the hospital, while the remaining 10 were lost to follow-up. Among the participants, 34.5% received HIV test for the first time. Especially in those aged 20-29, 46.0% were first time HIV testers.

conclusionsThe prevalence of HIV infection in the study population was 3.04%. The high collection suggested a demand for this type of testing in MSM. The test should be expanded further to difficult-to-reach or hidden populations.

trial registrationThis study was registered with the University Hospital Medical Information Network Clinical Trial Registry in August 20th, 2015 (Registry number: UMIN000018699 ).

Indexed as

Dried Blood Spot TestingPostal ServiceAdultBlood Specimen CollectionHIVHIV InfectionsHomosexuality, MaleHumansJapanMaleMass ScreeningMiddle AgedPrevalenceReagent Kits, DiagnosticSelf CareSexual and Gender MinoritiesReagent Kits, DiagnosticDried blood spotHIV prevalenceMSMSelf-collection kit

Identifiers

PMID30518333
PMCPMC6282288
OpenAlexW2902369006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.