Evidence map›Paper›PMID 30518174›Full record

ArticleMolecules and cells2019

Hepatitis B Virus X Protein Stimulates Virus Replication Via DNA Methylation of the C-1619 in Covalently Closed Circular DNA.

Hyehyeon Lee, Hyerin Jeong, Sun Young Lee, Soo Shin Kim, Kyung Lib Jang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules and cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. The role of HBV cccDNA in occult hepatitis B virus infection.Molecular and cellular biochemistry · 2023
    Review
  2. Relevance of HBx for Hepatitis B Virus-Associated Pathogenesis.International journal of molecular sciences · 2023
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hyehyeon LeeDepartment of Microbiology, College of Natural Science, Pusan National University, Busan 46241, Korea.
Hyerin JeongDepartment of Microbiology, College of Natural Science, Pusan National University, Busan 46241, Korea.
Sun Young LeeDepartment of Microbiology, College of Natural Science, Pusan National University, Busan 46241, Korea.
Soo Shin KimDepartment of Microbiology, College of Natural Science, Pusan National University, Busan 46241, Korea.
Kyung Lib JangDepartment of Microbiology, College of Natural Science, Pusan National University, Busan 46241, Korea.
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylation of HBV cccDNA has been detected

Indexed as

Binding SitesCytosineDNA-Binding ProteinsDNA, CircularDNA (Cytosine-5-)-MethyltransferasesDNA MethylationGenome, ViralHepatitis B virusHep G2 CellsHumansPromoter Regions, GeneticTrans-ActivatorsViral Regulatory and Accessory ProteinsVirus ReplicationCytosineDNA-Binding ProteinsDNA, CircularDNA (Cytosine-5-)-Methyltransferaseshepatitis B virus X proteinTrans-ActivatorsViral Regulatory and Accessory Proteinscovalently closed circular DNADNA methylationHBxhepatitis B virusnegative regulatory region binding protein

Identifiers

PMID30518174
PMCPMC6354056
OpenAlexW2963575615

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.