Evidence map›Paper›PMID 30518158›Full record

ArticleInternational journal of molecular sciences2018

Tissue-Specific Down-Regulation of the Long Non-Coding RNAs PCAT18 and LINC01133 in Gastric Cancer Development.

Kobra Foroughi, Mohammad Amini, Amir Atashi, Habibollah Mahmoodzadeh, Ute Hamann, Mehdi Manoochehri

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 48 citations in OpenAlex.

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  13. A review on the role of LINC01133 in cancers.Cancer cell international · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Kobra ForoughiSchool of Medicine, Shahroud University of Medical Sciences, Shahroud 3614773955, Iran. k.forughi@shmu.ac.ir.
Mohammad AminiSchool of Medicine, Shahroud University of Medical Sciences, Shahroud 3614773955, Iran. mohammadamini0624@gmail.com.ORCID 0000-0001-7543-9577
Amir AtashiDepartment of Medical Laboratory Sciences, School of Allied Medical Sciences, Shahroud University of Medical Sciences, Shahroud 3614773955, Iran. atashia@shmu.ac.ir.
Habibollah MahmoodzadehDepartment of Surgery, Cancer Institute, Tehran University of Medical Sciences, Tehran 6718743161, Iran. hmahmoodzadeh@tums.ac.ir.
Ute HamannMolecular Genetics of Breast Cancer (B072), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. u.hamann@dkfz-heidelberg.de.
Mehdi ManoochehriSchool of Medicine, Shahroud University of Medical Sciences, Shahroud 3614773955, Iran. m.manoochehri@dkfz.de.
Shahroud University of Medical Sciences · IRGerman Cancer Research Center · DETehran University of Medical Sciences · IR

Funding

Shahroud University of Medical Sciences 9559
6 · The paper itself

Abstract

Gastric cancer (GC) is the fifth most common cancer and the third most frequent cause of cancer deaths worldwide. The high death rate associated with GC, and lack of appropriate biomarkers for diagnosis, prognosis, and treatment emphasize the need for identification of novel molecules. Given the emerging roles for long non-coding RNAs (lncRNAs) in cancer development, we studied novel lncRNA candidates involved in gastric carcinogenesis. LncRNA candidate discovery was performed using analyses of available datasets and literature. Validation was done using an internal sample set of GC/normal tissues, and external independent datasets. Network analysis and functional annotation of co-expressed protein coding genes were performed using the weighted gene correlation network analysis (WGCNA) and ingenuity pathway analysis. Two novel lncRNAs,

Indexed as

Gene Expression Regulation, NeoplasticAdenocarcinomaCarcinogenesisDown-RegulationGene Regulatory NetworksHumansMiddle AgedMolecular Sequence AnnotationOrgan SpecificityRNA, Long NoncodingStomach Neoplasmslong non-coding RNA LINC01133, humanRNA, Long Noncodinggastric cancergene expressionGEO and TCGA databaseslong noncoding RNAtumor suppressor

Identifiers

PMID30518158
PMCPMC6321575
OpenAlexW2902831422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.