ArticleCell reports2018
tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
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Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
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64citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
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Who cites it
64 citing papers in PubMed, 97 citations in OpenAlex.
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- Observing intersubunit dynamics in single yeast ribosomes.Nucleic acids research · 2026Article
- Structural studies of nedicistrovirus IRES-driven, initiation factor-independent translation shed light on key steps of eukaryotic translation elongation.Nucleic acids research · 2026Article
- rRNA expansion segments mediate ribosome dimerization as a conserved stress response.Nucleic acids research · 2026Article
- The ribosome derives the energy to translocate and unwind mRNA from EF-G binding.Nature communications · 2025Article
- Structural mechanism of mRNA decoding by mammalian GTPase GTPBP1.Nature communications · 2025Article
- Near-cognate tRNAs enhance tRNA rejection and prime the ribosome for rapid subsequent tRNA testing.Biophysical journal · 2025Article
- Ribosomal Architecture and rRNA Modification Landscape in the Tick-Borne ParasitebioRxiv : the preprint server for biology · 2025Article
- Structural Studies of Nedicistrovirus IRES-Driven, Initiation Factor-independent Translation Shed Light on Key Steps of Eukaryotic Translation Elongation.bioRxiv : the preprint server for biology · 2025Article
- Structural mechanism of mRNA decoding by mammalian GTPase GTPBP1.bioRxiv : the preprint server for biology · 2025Article
- Profiling of terminating ribosomes reveals translational control at stop codons.bioRxiv : the preprint server for biology · 2025Article
- Doublet decoding of tRNANature communications · 2025Article
- Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering.RNA (New York, N.Y.) · 2025Article
- Capturing eukaryotic ribosome dynamics in situ at high resolution.Nature structural & molecular biology · 2025Article
- Visualizing the modification landscape of the human 60S ribosomal subunit at close to atomic resolution.Nucleic acids research · 2025Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 2 countries.
Julia FlisInstitut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Mikael HolmDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
Emily J RundletDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA; Tri-Institutional PhD Program in Chemical Biology, Weill Cornell Medicine, New York, NY, USA.
Justus LoerkeInstitut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Tarek HilalInstitut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Marylena DabrowskiInstitut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Jörg BürgerInstitut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany; UltraStrukturNetzwerk, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany.
Thorsten MielkeUltraStrukturNetzwerk, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany.
Scott C BlanchardDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA; Tri-Institutional PhD Program in Chemical Biology, Weill Cornell Medicine, New York, NY, USA. Electronic address: scb2005@med.cornell.edu.
Christian M T SpahnInstitut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: christian.spahn@charite.de.
Tatyana V BudkevichInstitut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: tetyana.budkevych@charite.de.
Charité - Universitätsmedizin Berlin · DEMax Planck Institute for Molecular Genetics · DECornell University · USTri-Institutional PhD Program in Chemical Biology · USWeill Cornell Medicine · US
Funding
Imaging Protein Synthesis on the Ribosome using Single-Molecule FRETR01GM079238 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI BLANCHARD, SCOTT C · 2006 to 2023
$7.0MNext-generation Fluorescent Probes for Biological ResearchR01GM098859 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI BLANCHARD, SCOTT C · 2012 to 2019
$2.9MTri-Institutional PhD Program in Chemical BiologyT32GM115327 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI TAN, DEREK S · 2015 to 2019
$741kNIGMS NIH HHS R01 GM079238NIGMS NIH HHS R01 GM098859NIGMS NIH HHS T32 GM115327
Abstract
Translocation moves the tRNA
Indexed as
AnimalsBacteriaGuanosine TriphosphateHumansHydrolysisInternal Ribosome Entry SitesMammalsModels, MolecularPeptide Elongation Factor 2Protein DomainsRibosomesRNA, MessengerRNA, TransferGuanosine TriphosphateInternal Ribosome Entry SitesPeptide Elongation Factor 2RNA, MessengerRNA, Transfercryo-EMEF-Gelongation factor eEF2large-scale conformational changesmacromolecular machinemammalian ribosomesmFRETtranslation elongationtranslocation
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.