Evidence map›Paper›PMID 30517851›Full record

ReviewLife sciences2019

A systematic comparison of exercise training protocols on animal models of cardiovascular capacity.

Rui Feng, Liyang Wang, Zhonguang Li, Rong Yang, Yu Liang, Yuting Sun, Qiuxia Yu, George Ghartey-Kwansah, Yanping Sun, Yajun Wu and 8 more

Erratum issuedAbstract readReview
In one paragraph

Review in Life sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Molecular mechanism on autophagy associated cardiovascular dysfunction inFrontiers in cell and developmental biology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. The role of autophagy in the progression of HIV infected cardiomyopathy.Frontiers in cell and developmental biology · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Senescence in Vascular Smooth Muscle Cells and Atherosclerosis.Frontiers in cardiovascular medicine · 2022
    Review
  16. Review
  17. Article
  18. Accelerating theLife (Basel, Switzerland) · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 3 countries.

Rui FengNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China.
Liyang WangNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Zhonguang LiNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China; Ohio State University School of Medicine, Columbus, OH 43210, USA.
Rong YangNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China.
Yu LiangNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China.
Yuting SunNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China.
Qiuxia YuNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China.
George Ghartey-KwansahNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China; Department of Biomedical Sciences, College of Health and Allied Sciences, University of Cape Coast, Ghana.
Yanping SunCollege of Pharmacy, Xi'an Medical University, Xi'an 710062, China.
Yajun WuNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China.
Wei ZhangNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China.
Xin ZhouNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China; Ohio State University School of Medicine, Columbus, OH 43210, USA.
Mengmeng XuDepartment of Pharmacology, Duke University Medical Center, Durham, NC 27708, USA.
Joseph BryantUniversity of Maryland School of Medicine, Baltimore, MD 21287, USA.
Guifang YanJohns Hopkins School of Medicine, Baltimore, MD 21287, USA.
William IsaacsJohns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Jianjie MaOhio State University School of Medicine, Columbus, OH 43210, USA.
Xuehong XuNational Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China. Electronic address: xhx0708@snnu.edu.cn.
Shaanxi Normal University · CNJohns Hopkins University · USDuke Medical Center · USHarvard University · USThe Ohio State University · USUniversity of Cape Coast · GHUniversity of Maryland, Baltimore · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2M
Targeting cell membrane repair for treatment of acute kidney injuryR01DK106394 · NIDDK · OHIO STATE UNIVERSITY · PI LIN, PEI-HUI, ROVIN, BRAD H · 2016 to 2020
$2.5M
Myokine function of MG53 in muscle injury-repair and regenerationR01AR070752 · NIAMS · OHIO STATE UNIVERSITY · PI HAN, RENZHI · 2017 to 2021
$1.7M
NIAMS NIH HHS R01 AR070752NIDDK NIH HHS R01 DK106394NIGMS NIH HHS T32 GM007171
6 · The paper itself

Abstract

Cardiovascular disease (CVD) is a major global cause of mortality, which has prompted numerous studies seeking to reduce the risk of heart failure and sudden cardiac death. While regular physical activity is known to improve CVD associated morbidity and mortality, the optimal duration, frequency, and intensity of exercise remains unclear. To address this uncertainty, various animal models have been used to study the cardioprotective effects of exercise and related molecular mechanism such as the mice training models significantly decrease size of myocardial infarct by affecting Kir6.1, VSMC sarc-K

Indexed as

AnimalsCardiovascular DiseasesDisease Models, AnimalExerciseExercise TherapyHeartHumansMyocardiumPhysical Conditioning, AnimalStress, PhysiologicalAnimal modelExercise-promoted cardio-protectionExercise stress testingExercise training procedure

Identifiers

PMID30517851
PMCPMC6320317
OpenAlexW2902880165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.