ArticleThe Journal of clinical endocrinology and metabolism2019
BMI Change During Puberty Is an Important Determinant of Adult Type 2 Diabetes Risk in Men.
Article in The Journal of clinical endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Incidence and temporal trends in type 2 diabetes by weight status: A systematic review and meta-analysis of prospective cohort studies.Journal of global health · 2023Pooled it
- Association of weight status and the risks of diabetes in adults: a systematic review and meta-analysis of prospective cohort studies.International journal of obesity (2005) · 2022Pooled it
- Six decades of trends in BMI, thinness, overweight, and obesity among 210,927 Swedish children in different socioeconomic contexts.BMC public health · 2026Article
- Childhood obesity: The threatening apprentice of the adiposity empire.Reviews in endocrine & metabolic disorders · 2025Review
- Prepuberty is a window period for curcumin to prevent obesity in postnatal overfed rats.Pediatric research · 2024Article
- Low birthweight and overweight during childhood and young adulthood and the risk of type 2 diabetes in men: a population-based cohort study.Diabetologia · 2024Article
- Randomized control trial of a childhood obesity prevention family-based program: "Abriendo Caminos" and effects on BMI.Frontiers in pediatrics · 2023Article
- Pediatric obesity-Long-term consequences and effect of weight loss.Journal of internal medicine · 2022Review
- Single Point Insulin Sensitivity Estimator for predicting type 2 diabetes mellitus in obese adolescents.Annals of pediatric endocrinology & metabolism · 2022Article
- Novel type of references for BMI aligned for onset of puberty - using the QEPS growth model.BMC pediatrics · 2022Article
- Body mass index in adolescence, risk of type 2 diabetes and associated complications: A nationwide cohort study of men.EClinicalMedicine · 2022Article
- A review on interplay between obesity, lipoprotein profile and nutrigenetics with selected candidate marker genes of type 2 diabetes mellitus.Molecular biology reports · 2022Review
- Time trends of overweight and obesity among schoolchildren in Kuwait over a 13-year period (2007-2019): repeated cross-sectional study.Public health nutrition · 2021Article
- Early puberty and risk for type 2 diabetes in men.Diabetologia · 2020Article
- Pubertal timing and adult fracture risk in men: A population-based cohort study.PLoS medicine · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to determine the role of change in body mass index (BMI) during puberty, independent of childhood overweight, for risk of adult type 2 diabetes in men. STUDY DESIGN, POPULATION, AND OUTCOME: We included 36,176 men who had weight and height measured at age 8 and 20 years available from the BMI Epidemiology Study and the Conscription register. Information on type 2 diabetes (n = 1,777) was retrieved from the Swedish National Patient Register. Hazard ratios and 95% CIs were estimated by Cox regressions including birth year and country of birth as covariates. Because the assumption of proportional hazards was violated for the association between BMI change during puberty and type 2 diabetes, we split the follow-up time into early (≤55.7 years) and late (>55.7 years).
resultsBoth childhood overweight and high BMI increase during puberty associated with risk of adult type 2 diabetes. Men with childhood overweight that normalized during puberty did not have significantly increased risk of type 2 diabetes [early type 2 diabetes 1.28 (0.89; 1.82); late type 2 diabetes 1.35 (0.97; 1.87)]. Men who developed overweight during puberty [early 4.67 (3.90; 5.58); late 2.85 (2.25; 3.61)] and men overweight throughout childhood and puberty [early 4.82 (3.84; 6.05); late 3.04 (2.27; 4.06)] had substantially increased risk of type 2 diabetes compared with men who were never overweight.
conclusionBMI change during puberty is an important and childhood BMI a modest independent determinant of adult type 2 diabetes risk in men.
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Registered trials
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