ArticleDepression and anxiety2019
Developmental changes in resting-state functional networks among individuals with and without internalizing psychopathologies.
Article in Depression and anxiety, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Anticipation of monetary reward in amygdala, insula, caudate are predictors of pleasure sensitivity to d-Amphetamine administration.Drug and alcohol dependence · 2020Trial
- Age differences in electrocortical reactivity to fearful faces following aversive conditioning in youth.Journal of experimental child psychology · 2019Trial
- Changes in resting-state functional connectivity between large-scale brain networks after an intensive arts intervention for adolescents with depression.Translational psychiatry · 2026Article
- Attenuated cognitive control network connectivity as a mechanism in mother-daughter intergenerational transmission of depression: a preliminary study.Scientific reports · 2025Article
- Reduced volume of the left cerebellar lobule VIIb and its increased connectivity within the cerebellum predict more general psychopathology one year later via worse cognitive flexibility in children.Developmental cognitive neuroscience · 2023Article
- Using Network Parcels and Resting-State Networks to Estimate Correlates of Mood Disorder and Related Research Domain Criteria Constructs of Reward Responsiveness and Inhibitory Control.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- Intrinsic functional connectivity in families genetically enriched for social anxiety disorder - an endophenotype study.EBioMedicine · 2021Article
- Coordination between frontolimbic resting state connectivity and hypothalamic-pituitary-adrenal axis functioning in adolescents with and without depression.Psychoneuroendocrinology · 2021Article
- Research Review: Brain network connectivity and the heterogeneity of depression in adolescence - a precision mental health perspective.Journal of child psychology and psychiatry, and allied disciplines · 2020Review
- A Lifespan Model of Interference Resolution and Inhibitory Control: Risk for Depression and Changes with Illness Progression.Neuropsychology review · 2020Review
- An Interactive Developmental Neuroscience Perspective on Adolescent Resilience to Familial Depression.JAMA psychiatry · 2018Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThree well-established intrinsic connectivity networks (ICNs) involved in cognitive-affective processing include the cognitive control network (CCN), default mode network (DMN), and salience and emotional network (SEN). Despite recent advances in understanding developmental changes in these ICNs, the majority of research has focused on single seeds or networks in isolation with limited age ranges. Additionally, although internalizing psychopathologies (IPs), such as anxiety and depression, are often characterized by maladaptive cognitive-affective processing styles, it is not clear how IP history influences age-related changes in brain networks.
methodThe current study aimed to characterize the normative development of the CCN, DMN, and SEN across a large age-span (7-29 year olds) of typically developing (TD) individuals (n = 97). We also explore how age may impact differences in network connectivity between TD individuals and patients with IPs (n = 136).
resultsAmong TD individuals, DMN and CCN connectivity strengthened with age, whereas connectivity between the SEN and ventromedial prefrontal cortex weakened across development. When exploring group (IP vs. TD) differences, the IP group was characterized by greater connectivity between the CCN and cerebellum and between the SEN and caudate from childhood to early adulthood, relative to TD individuals. In addition, patients with IPs, versus TD individuals, exhibited reduced connectivity between the SEN and medial frontal gyrus from adolescence to adulthood.
conclusionsThe current findings shed light on differential age-related changes in brain network patterns among psychiatrically free, TD individuals and those with internalizing disorders, and may provide plausible targets for novel mechanism-based treatments that differ based on developmental stage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.