Evidence map›Paper›PMID 30516087›Full record

ArticleCell cycle (Georgetown, Tex.)2018

Divergent impact of actin isoforms on cell cycle regulation.

Vera Dugina, Galina Shagieva, Natalya Khromova, Pavel Kopnin

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. The Cytoplasmic Actins in the Regulation of Endothelial Cell Function.International journal of molecular sciences · 2021
    Review
  11. Article
  12. Article
  13. Regulation of actin isoforms in cellular and developmental processes.Seminars in cell & developmental biology · 2020
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Vera Duginaa Belozersky Institute of Physico-Chemical Biology , Lomonosov Moscow State University , Moscow , Russia.ORCID http://orcid.org/0000-0002-7618-5959
Galina Shagievaa Belozersky Institute of Physico-Chemical Biology , Lomonosov Moscow State University , Moscow , Russia.ORCID http://orcid.org/0000-0001-7702-4690
Natalya Khromovab Blokhin Russian Cancer Research Center , Moscow , Russia.
Pavel Kopninb Blokhin Russian Cancer Research Center , Moscow , Russia.ORCID http://orcid.org/0000-0002-2078-4274
Lomonosov Moscow State University · RURussian Cancer Research Center NN Blokhin · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have shown that cytoplasmic actin isoforms play different roles in neoplastic cell transformation. β-Cytoplasmic actin acts as a tumor suppressor, affecting epithelial differentiation, cell growth, cell invasion and tumor growth of colon and lung carcinoma cells. In contrast, γ-cytoplasmic actin enhances malignant features of tumor cells whose actin network regulation is carried out

Indexed as

actin isoformsCancercyclinsERK1/2

Identifiers

PMID30516087
PMCPMC6300101
OpenAlexW2905440155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.