ArticleHuman brain mapping2019
Tracking the dynamic functional connectivity structure of the human brain across the adult lifespan.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of global signal topography in aging, neuropsychiatric disorders, and cognitive task performance.Brain imaging and behavior · 2026Pooled it
- The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large-scale resting-state functional brain networks in aging.Psychophysiology · 2023Pooled it
- Inter-individual differences in baseline dynamic functional connectivity are linked to cognitive aftereffects of tDCS.Scientific reports · 2022Trial
- Age-dependent modulations of hemispheric small-world networks in different eye states: resting-state electroencephalogram research.GeroScience · 2026Article
- Investigating the Contribution of Molecular-Enriched Functional Connectivity to Brain-Age Analysis.Human brain mapping · 2026Article
- Variation in high-amplitude events across the human lifespan.Network neuroscience (Cambridge, Mass.) · 2026Article
- Investigating the Contribution of Molecular-Enriched Functional Connectivity to Brain-Age Analysis.bioRxiv : the preprint server for biology · 2025Article
- Sex effects on dynamic structure-function coupling of intrinsic brain network.Brain imaging and behavior · 2025Article
- Dynamic Functional Connectivity Markers in Anorexia Nervosa and Their Association With Clinical Symptoms: A Cross-Sectional Study.European eating disorders review : the journal of the Eating Disorders Association · 2025Article
- Dynamic Functional Connectivity Between Amygdala and Cognitive Control Network Predicts Delay Discounting in Older Adolescents.Human brain mapping · 2025Article
- The lifelong nonlinear development of spatial variability of brain signals.Communications biology · 2025Article
- Dynamic fluctuations of intrinsic brain activity are associated with consistent topological patterns in puberty and are biomarkers of neural maturation.Network neuroscience (Cambridge, Mass.) · 2025Article
- Effects of an 18-month meditation training on dynamic functional connectivity states in older adults: Secondary analyses from the Age-Well randomized controlled trial.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- A signature combining brain functional connectivity with executive and motor function for general cognitive decline in Parkinson's disease.Frontiers in neurology · 2025Article
- Investigating robust associations between functional connectivity based on graph theory and general intelligence.Scientific reports · 2024Article
- Higher general intelligence is associated with stable, efficient, and typical dynamic functional brain connectivity patterns.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Neuroimaging and plasma evidence of early white matter loss in Parkinson's disease with poor outcomes.Brain communications · 2024Article
- Spatiotemporal dedifferentiation of the global brain signal topography along the adult lifespan.Human brain mapping · 2023Article
- White-matter degradation and dynamical compensation support age-related functional alterations in human brain.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Age-dependent changes in the dynamic functional organization of the brain at rest: a cross-cultural replication approach.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The transition from early adulthood to the elder is marked by functional and structural brain transformations. Many previous studies examined the correlation between the functional connectivity (FC) and aging using resting-state fMRI. Results showed that the changes in FC are linked to aging as well as the cognitive ability changes. However, some researchers proposed that the FC is not static but dynamic changes during the resting-state fMRI scan. In this study, we examined the correlation between the resting-state dynamic functional network connectivity and age using resting scan data of 434 subjects. The results suggested: (a) age is negatively associated with variability of dynamic functional network connectivity state; (b) the dwell time of each age range spends in each state is different; (c) the dynamic graph metrics curve of each age ranges is different and 19-30 age range has the largest average global efficiency and average local efficiency; (d) some dynamic functional network connectivity measures were correlated to the certain cognitive ability. Overall, the results suggested the changes in dynamic functional network connectivity measures may be a characteristic of the aging process and in further investigations may provide a deep understanding of the aging process.
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Registered trials
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