SynthesisClinical cardiology2019
Impact of tricuspid regurgitation and right ventricular dysfunction on outcomes after transcatheter aortic valve replacement: A systematic review and meta-analysis.
Synthesis in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Tricuspid Regurgitation and Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis.Arquivos brasileiros de cardiologia · 2023Pooled it
- Impact of tricuspid regurgitation and right ventricular dysfunction on outcomes after transcatheter aortic valve replacement: A systematic review and meta-analysis.Clinical cardiology · 2019Pooled it
- Association of the hemoglobin-to-red cell distribution width ratio with clinical outcomes after transcatheter aortic valve implantation.Journal of geriatric cardiology : JGC · 2026Article
- Indications and Outcomes of Non-Emergent Cardiac Surgery Following Transcatheter Aortic Valve Replacement.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Natural History of Tricuspid Regurgitation After Transcatheter Aortic Valve Implantation.Journal of the American Heart Association · 2025Observational
- One-Year Outcome of Patients Undergoing Transcatheter Aortic Valve Replacement with Concomitant SignificantTricuspid Regurgitation.Journal of cardiovascular development and disease · 2025Article
- Impact of Right Heart Failure on Outcomes of Transcatheter Aortic Valve Implantation: Insights from the National Inpatient Sample.Journal of clinical medicine · 2025Article
- Multiple Valvular Heart Disease in the Transcatheter Era: A State-of-the-Art Review.Structural heart : the journal of the Heart Team · 2024Review
- Aortic Stenosis and the Evolution of Cardiac Damage after Transcatheter Aortic Valve Replacement.Journal of clinical medicine · 2024Article
- Functional Tricuspid Regurgitation in the Transcatheter Aortic Valve Replacement Population and Emerging Transcatheter Tricuspid Valve Interventions.US cardiology · 2024Review
- The Forgotten Valve is not to be Forgiven: Tricuspid Regurgitation Impact on Clinical Outcomes after Transcatheter Aortic Valve Implantation.Arquivos brasileiros de cardiologia · 2023Article
- Prognostic relevance of mitral and tricuspid regurgitation after transcatheter aortic valve implantation: Impact of follow-up time point for decision-making.Frontiers in cardiovascular medicine · 2023Article
- Tricuspid Valve Percutaneous Therapies.Current cardiology reports · 2022Review
- Pre-Procedural Right Ventricular Longitudinal Strain and Post-Procedural Tricuspid Regurgitation Predict Mortality in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI).Journal of clinical medicine · 2021Article
- The Prognosis of Baseline Mitral Regurgitation in Patients with Transcatheter Aortic Valve Implantation.Journal of clinical medicine · 2021Article
- Feasibility of Transcatheter Caval Valve Implantation to ImproveFrontiers in cardiovascular medicine · 2021Article
- Transcatheter aortic valve implantation-related futility: prevalence, predictors, and clinical risk model.Heart and vessels · 2020Observational
- Late Progression of Tricuspid Regurgitation After Transcatheter Aortic Valve Replacement.Journal of the Society for Cardiovascular Angiography & InterventionsArticle
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Far less attention has been paid to the prognostic effect of right-side heart disease on outcomes after transcatheter aortic valve replacement (TAVR) when compared with the left side. Therefore, we performed a systematic review and meta-analysis on the impact of tricuspid regurgitation (TR) and right ventricular (RV) dysfunction on outcomes after TAVR. We hypothesized that TR and RV dysfunction may have a deleterious effect on outcomes after TAVR. Article revealing the prognostic effect of TR and RV dysfunction on outcomes after TAVR were being integrated. Random or fixed effect model was adopted in accordance with the heterogeneity. There were nine studies with a total of 6466 patients enrolled after a comprehensive literature search of the MEDLINE/PubMed, EMBASE, ISI Web of Science, and Cochrane databases. The overall analysis revealed that moderate or severe TR at baseline increased all-cause mortality after TAVR (HR = 1.79, CI 95% 1.52-2.11, P < 0.001). Both baseline RV dysfunction (HR = 1.53, CI 95% 1.27-1.83, P < 0.001) and presence of RV dilation (HR = 1.83, CI 95% 1.47-2.27, P < 0.001) were associated with all-cause mortality. Both baseline moderate or severe TR and RV dysfunction worsen prognosis after TAVR and careful assessment of right heart function should be done for clinical decision by the heart team before the TAVR procedure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.