Evidence map›Paper›PMID 30515684›Full record

ArticleEnvironmental science and pollution research international2019

Comparison of Prioritisation Schemes for Human Pharmaceuticals in the Aquatic Environment.

Sarah Letsinger, Paul Kay

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Environmental science and pollution research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 34 citations in OpenAlex.

  1. Impact of therapeutic pharmaceuticals on water bodies: diagnosis, ecological threat, and removal strategies.Water science and technology : a journal of the International Association on Water Pollution Research · 2025
    Article
  2. Article
  3. Article
  4. Antibacterials in Aquatic Environment and Their Toxicity to Fish.Pharmaceuticals (Basel, Switzerland) · 2020
    Review
  5. Norm index-based QSPR model for describing the n-octanol/water partition coefficients of organics.Environmental science and pollution research international · 2020
    Article
  6. Sorption of ionic and neutral species of pharmaceuticals to loessial soil amended with biochars.Environmental science and pollution research international · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sarah LetsingerSchool of Geography, University of Leeds, Woodhouse Lane, Leeds, West Yorkshire, LS2 9JT, UK. gysle@leeds.ac.uk.ORCID http://orcid.org/0000-0001-6211-8918
Paul KaySchool of Geography, University of Leeds, Woodhouse Lane, Leeds, West Yorkshire, LS2 9JT, UK.
University of Leeds · GB

Funding

Natural Environment Research Council 165232
6 · The paper itself

Abstract

Only a small proportion of pharmaceuticals available for commercial use have been monitored in the aquatic environment, and even less is known about the effects on organisms. With thousands of pharmaceuticals in use, it is not feasible to monitor or assess the effects of all of these compounds. Prioritisation schemes allow the ranking of pharmaceuticals based on their potential as environmental contaminants, allowing resources to be appropriately used on those which are most likely to enter the environment and cause greatest harm. Many different types of prioritisation schemes exist in the literature and those utilising predicted environmental concentrations (PECs), the fish plasma model (FPM), critical environmental concentrations (CECs) and acute ecotoxicological data were assessed in the current study using the 50 most prescribed drugs in the UK. PECs were found to be overestimates of mean measured environmental concentrations but mainly underestimations of maximum concentrations. Acute ecological data identified different compounds of concern to the other effects assessments although the FPM and CECs methods were more conservative. These schemes highlighted antidepressants, lipid regulators, antibiotics, antihypertensive compounds and ibuprofen as priority compounds for further study and regulation.

Indexed as

AnimalsAntidepressive AgentsEcotoxicologyEnvironmental MonitoringFishesHumansIbuprofenPharmaceutical PreparationsRisk AssessmentUnited KingdomWater Pollutants, ChemicalAntidepressive AgentsIbuprofenPharmaceutical PreparationsWater Pollutants, ChemicalFPMPECPharmaceuticalsPrioritisationRankingToxicity

Identifiers

PMID30515684
PMCPMC6513794
OpenAlexW2902401026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.