Evidence map›Paper›PMID 30515641›Full record

ArticleMagma (New York, N.Y.)2019

A phase-cycled temperature-sensitive fast spin echo sequence with conductivity bias correction for monitoring of mild RF hyperthermia with PRFS.

Mingming Wu, Hendrik T Mulder, Yuval Zur, Silke Lechner-Greite, Marion I Menzel, Margarethus M Paulides, Gerard C van Rhoon, Axel Haase

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Mingming WuMunich School of Bioengineering, Technical University of Munich, Boltzmannstr. 11, 85748, Garching bei München, Germany. mingming.wu@tum.de.ORCID http://orcid.org/0000-0002-8593-7091
Hendrik T MulderErasmus MC Cancer Institute, Rotterdam, The Netherlands.
Yuval ZurGE Healthcare, Haifa, Israel.
Silke Lechner-GreiteGE Healthcare, Munich, Germany.
Marion I MenzelGE Healthcare, Munich, Germany.
Margarethus M PaulidesErasmus MC Cancer Institute, Rotterdam, The Netherlands.
Gerard C van RhoonErasmus MC Cancer Institute, Rotterdam, The Netherlands.
Axel HaaseMunich School of Bioengineering, Technical University of Munich, Boltzmannstr. 11, 85748, Garching bei München, Germany.
Erasmus MC Cancer Institute · NLSiemens Healthineers (Germany) · DETechnical University of Munich · DE

Funding

European Commission 605162
6 · The paper itself

Abstract

objectiveMild hyperthermia (HT) treatments are generally monitored by phase-referenced proton resonance frequency shift calculations. A novel phase and thus temperature-sensitive fast spin echo (TFSE) sequence is introduced and compared to the double echo gradient echo (DEGRE) sequence. THEORY AND

methodsFor a proton resonance frequency shift (PRFS)-sensitive TFSE sequence, a phase cycling method is applied to separate even from odd echoes. This method compensates for conductivity change-induced bias in temperature mapping as does the DEGRE sequence. Both sequences were alternately applied during a phantom heating experiment using the clinical setup for deep radio frequency HT (RF-HT). The B

resultsDuring the phantom heating experiment, on average TFSE temperature maps achieved double temperature-to-noise ratio (TNR) efficiency in comparison with DEGRE temperature maps. In-vivo images of the thighs exhibit stable temperature readings of ± 1 °C over 25 min of scanning in three volunteers for both methods. On average, the TNR efficiency improved by around 25% for in vivo data.

conclusionA novel TFSE method has been adapted to monitor temperature during mild HT.

Indexed as

ProtonsRadio WavesElectric ConductivityEquipment DesignHot TemperatureHumansHyperthermia, InducedMagnetic Resonance ImagingPelvisPhantoms, ImagingSignal-To-Noise RatioThermographyProtonsConductivityDouble echo gradient echoFast spin echoHyperthermiaInterventionMR thermometryProton resonance frequency shift

Identifiers

PMID30515641
OpenAlexW2903195364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.