ReviewUrolithiasis2019
Cystinuria: genetic aspects, mouse models, and a new approach to therapy.
Review in Urolithiasis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Outcomes of Paediatric Cystine Stone Management: Results of a Systematic Review.Current urology reports · 2023Pooled it
- Outcomes and Long-term Follow-up of Patients with Cystine Stones: a Systematic Review.Current urology reports · 2019Pooled it
- Trial
- Gene modification: Exploring the potential in treating kidney diseases.Pharmacological research · 2026Review
- Cystinuria: Diagnosis, Medical and Surgical Management, and Emerging Therapies. A Narrative Review.Research and reports in urology · 2026Review
- Inborn Errors of Amino Acid Metabolism Revisited: Clinical Implications and Insights into Current Therapies.Journal of clinical medicine · 2025Review
- Partial correction of cystinuria type A in mice via kidney-targeted transposon delivery.Molecular therapy. Nucleic acids · 2025Article
- Nephrotic Syndrome Induced by Tiopronin in a Male Patient with Cystinuria.Balkan journal of medical genetics : BJMG · 2025Article
- A Case of Cystinuria With Compound Heterozygous Mutations Both inElectrolyte & blood pressure : E & BP · 2025Article
- Mitochondrial SLC3A1 regulates sexual dimorphism in cystinuria.Genes & diseases · 2025Article
- Cystinuria in children: diagnosis and treatment.World journal of urology · 2025Review
- The role of double heterozygotes of SLC3A1 and SLC7A9 in the prevalence of cystine stones.Genetics in medicine : official journal of the American College of Medical Genetics · 2025Article
- Nineteenth Century Amorphous Calcium Carbonate.Crystal growth & design · 2024Review
- SLC7A9 suppression increases chemosensitivity by inducing ferroptosis via the inhibition of cystine transport in gastric cancer.EBioMedicine · 2024Article
- Structure-activity relationships and pharmacokinetic evaluation of L-cystine diamides as L-cystine crystallization inhibitors for cystinuria.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2024Article
- 8-l-Cystinyl Bis(1,8-diazaspiro[4.5]decane) as an Orally Bioavailable l-Cystine Crystallization Inhibitor for Cystinuria.ACS medicinal chemistry letters · 2024Article
- Molecular Variability in Levodopa Absorption and Clinical Implications for the Management of Parkinson's Disease.Journal of Parkinson's disease · 2024Review
- Novel compound heterozygous pathogenic variants in the SLC3A1 gene in a Chinese family with cystinuria.BMC medical genomics · 2023Article
- Clinical Course and Mutational Analysis of Patients with Cystine Stone: A Single-Center Experience.Biomedicines · 2023Article
- Population genetics analysis of SLC3A1 and SLC7A9 revealed the etiology of cystine stone may be more than what our current genetic knowledge can explain.Urolithiasis · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Cystinuria, a genetic disorder of cystine transport, is characterized by excessive excretion of cystine in the urine and recurrent cystine stones in the kidneys and, to a lesser extent, in the bladder. Males generally are more severely affected than females. The disorder may lead to chronic kidney disease in many patients. The cystine transporter (b
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.