ArticleAmerican journal of speech-language pathology2019
Estimates of the Prevalence of Speech and Motor Speech Disorders in Youth With 22q11.2 Deletion Syndrome.
Article in American journal of speech-language pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
- Otolaryngologic disease in 22q11.2 deletion syndrome: spectrum, co-occurrence, and outcomes in a contemporary pediatric cohort.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Development of Speech and Communication in Polish Children with 22q11.2 Deletion Syndrome: A Cross-Sectional Study.Brain sciences · 2024Article
- Multiple Intestinal Anomalies in a Newborn with 22q11.2 Microdeletion Syndrome: A Case Report and Literature Review.Journal of pediatric genetics · 2024Article
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- Comorbidity and Severity in Childhood Apraxia of Speech: A Retrospective Chart Review.Journal of speech, language, and hearing research : JSLHR · 2023Article
- Review of methods for conducting speech research with minimally verbal individuals with autism spectrum disorder.Augmentative and alternative communication (Baltimore, Md. : 1985) · 2023Review
- The importance of deep speech phenotyping for neurodevelopmental and genetic disorders: a conceptual review.Journal of neurodevelopmental disorders · 2022Review
- The Relationship Between Single-Word Speech Severity and Intelligibility in Childhood Apraxia of Speech.Journal of speech, language, and hearing research : JSLHR · 2022Article
- Differences and Commonalities in Children with Childhood Apraxia of Speech and Comorbid Neurodevelopmental Disorders: A Multidimensional Perspective.Journal of personalized medicine · 2022Article
- Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome.Disease models & mechanisms · 2022Article
- Impact of Equine-Assisted Interventions on Heart Rate Variability in Two Participants with 22q11.2 Deletion Syndrome: A Pilot Study.Children (Basel, Switzerland) · 2021Article
- Characteristics of velopharyngeal dysfunction in 22q11.2 deletion syndrome: a retrospective case-control study.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2020Article
- Speech-Language Disorders in 22q11.2 Deletion Syndrome: Best Practices for Diagnosis and Management.American journal of speech-language pathology · 2019Review
- Estimates of the prevalence of motor speech disorders in children with idiopathic speech delay.Clinical linguistics & phonetics · 2019Article
- Estimates of the prevalence of speech and motor speech disorders in persons with complex neurodevelopmental disorders.Clinical linguistics & phonetics · 2019Article
- Initial studies of the phenotype and persistence of speech motor delay (SMD).Clinical linguistics & phonetics · 2019Article
- Estimates of the prevalence of speech and motor speech disorders in adolescents with Down syndrome.Clinical linguistics & phonetics · 2019Article
- Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Purpose Speech sound disorders and velopharyngeal dysfunction are frequent features of 22q11.2 deletion syndrome (22q). We report the first estimate of the prevalence of motor speech disorders (MSDs) in youth with 22q. Method Seventeen children and adolescents with 22q completed an assessment protocol that included a conversational speech sample. Data reduction included phonetic transcription, perceptual speech ratings, prosody-voice coding, and acoustic analyses. Data analyses included 3 motor speech measures and a cross-classification analytic. Prevalence estimates of speech and MSDs in youth with 22q were compared with estimates in speakers with other complex neurodevelopmental disorders: Down syndrome, fragile X syndrome, and galactosemia. Results Results indicated that 58.8% of the participants with 22q met criteria for speech delay, and 82.4% of the participants met criteria for MSDs, including 29.4% with speech motor delay, 29.4% with childhood dysarthria, 11.8% with childhood apraxia of speech, and 11.8% with concurrent childhood dysarthria and childhood apraxia of speech. MSDs were not significantly associated with velopharyngeal dysfunction. Conclusions In summary, 82.4% of the participants with 22q met criteria for 1 of 4 MSDs, predominantly speech motor delay and childhood dysarthria. Cross-validation of the present findings would support viewing MSDs as a core phenotypic feature of 22q.
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