Evidence map›Paper›PMID 30515171›Full record

Observational studyFrontiers in immunology2018

Autoantibodies to Peptidylarginine Deiminase 2 Are Associated With Less Severe Disease in Rheumatoid Arthritis.

Erika Darrah, Jon T Giles, Ryan L Davis, Pooja Naik, Hong Wang, Maximilian F Konig, Laura C Cappelli, Clifton O Bingham, Sonye K Danoff, Felipe Andrade

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Rheumatoid Arthritis: Biomarkers and the Latest Breakthroughs.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. The Lung in Rheumatoid Arthritis-Friend or Enemy?International journal of molecular sciences · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Erika DarrahDivision of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Jon T GilesDivision of Rheumatology, College of Physicians and Surgeons, Columbia University, New York, NY, United States.
Ryan L DavisDivision of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Pooja NaikDivision of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Hong WangDivision of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Maximilian F KonigDivision of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Laura C CappelliDivision of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Clifton O BinghamDivision of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Sonye K DanoffDivision of Pulmonary and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Felipe AndradeDivision of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Johns Hopkins University · USJohns Hopkins Medicine · USColumbia University · US

Funding

Inflammation and Cardiovascular Disease in Rheumatoid ArthritisR01AR050026 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI BATHON, JOAN MARIE · 2004 to 2022
$9.7M
Sample Processing and Immunoassay Research CoreP30AR070254 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI Antony Rosen · 2016 to 2026
$8.9M
NIAMS NIH HHS P30 AR070254NIAMS NIH HHS R01 AR050026
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedArthritis, RheumatoidAutoantibodiesBiomarkersCross ReactionsFemaleHumansMaleMiddle AgedProspective StudiesProtein-Arginine DeiminasesProtein-Arginine Deiminase Type 2Protein-Arginine Deiminase Type 4Severity of Illness IndexAutoantibodiesBiomarkersPADI2 protein, humanPADI4 protein, humanProtein-Arginine DeiminasesProtein-Arginine Deiminase Type 2Protein-Arginine Deiminase Type 4autoantibodiesautoimmunitydisease activityinterstitial lung diseasepeptidylarginine deiminaserheumatoid arthritisshared epitopeSharp score

Identifiers

PMID30515171
PMCPMC6255931
OpenAlexW2901827656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.