Evidence map›Paper›PMID 30515168›Full record

ArticleFrontiers in immunology2018

Delivery of IL-35 by

Massimo Maddaloni, Irina Kochetkova, Carol Hoffman, David W Pascual

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Interleukin-35: Structure, Function and Its Impact on Immune-Related Diseases.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2021
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Hsp65-ProducingFrontiers in immunology · 2020
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Massimo MaddaloniDepartment of Infectious Diseases and Immunology, University of Florida, Gainesville, FL, United States.
Irina KochetkovaDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, United States.
Carol HoffmanDepartment of Infectious Diseases and Immunology, University of Florida, Gainesville, FL, United States.
David W PascualDepartment of Infectious Diseases and Immunology, University of Florida, Gainesville, FL, United States.
University of Florida · USMontana State University · US

Funding

Regulatory Cell Therapy for Sjögren's Syndrome.R01DE026450 · NIDCR · UNIVERSITY OF FLORIDA · PI PASCUAL, DAVID W · 2017 to 2021
$1.8M
Regulatory Cell Therapy for Sjogrens SyndromeR56DE026450 · NIDCR · UNIVERSITY OF WYOMING · PI PASCUAL, DAVID W · 2023 to 2023
$351k
NIDCR NIH HHS R01 DE026450NIDCR NIH HHS R56 DE026450
6 · The paper itself

Abstract

IL-35, a relatively newly discovered cytokine belonging to the larger IL-12 family, shows unique anti-inflammatory properties, believed to be associated with dedicated receptors and signaling pathways. IL-35 plays a pivotal role in the development and the function of both regulatory B (Bregs) and T cells (Tregs). In order to further its therapeutic potential, a dairy

Indexed as

AnimalsArthritis, ExperimentalB-Lymphocytes, RegulatoryInterleukinsLactococcus lactisMaleMiceT-Lymphocytes, Regulatoryinterleukin-35, mouseInterleukinsCCR6cytokinesIL-10IL-35Lactococcusprobioticregulatory T cellstherapeutic

Identifiers

PMID30515168
PMCPMC6255909
OpenAlexW2901093676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.