Evidence map›Paper›PMID 30515157›Full record

Trial reportFrontiers in immunology2018

Antigen Specificity and Clinical Significance of IgG and IgA Autoantibodies Produced

Soizic Garaud, Pawel Zayakin, Laurence Buisseret, Undine Rulle, Karina Silina, Alexandre de Wind, Gert Van den Eyden, Denis Larsimont, Karen Willard-Gallo, Aija Linē

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. B cells in cancer: functions, mechanisms and therapeutic advances.Signal transduction and targeted therapy · 2026
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  6. CD4Cancer biology & medicine · 2026
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Soizic GaraudMolecular Immunology Unit, Institut Jules Bordet, Universite Libre de Bruxelles, Brussels, Belgium.
Pawel ZayakinCancer Biomarker and Immunotherapy Group, Latvian Biomedical Research and Study Centre, Riga, Latvia.
Laurence BuisseretMolecular Immunology Unit, Institut Jules Bordet, Universite Libre de Bruxelles, Brussels, Belgium.
Undine RulleInstitute of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.
Karina SilinaInstitute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
Alexandre de WindDepartment of Pathology, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
Gert Van den EydenTranslational Cancer Research Unit Antwerp, Oncology Centre, General Hospital Sint Augustinus, Wilrijk, Belgium.
Denis LarsimontDepartment of Pathology, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
Karen Willard-GalloMolecular Immunology Unit, Institut Jules Bordet, Universite Libre de Bruxelles, Brussels, Belgium.
Aija LinēCancer Biomarker and Immunotherapy Group, Latvian Biomedical Research and Study Centre, Riga, Latvia.
Université Libre de Bruxelles · BELatvian Biomedical Research and Study Centre · LVGZA Ziekenhuizen Campus Sint-Augustinus · BEInstitut Jules Bordet · BEUniversity Hospital of Zurich · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An important role for tumor infiltrating B lymphocytes (TIL-B) in the immune response to cancer is emerging; however, very little is known about the antigen specificity of antibodies produced

Indexed as

Antibody SpecificityAdultAgedAntigens, NeoplasmAutoantibodiesB-LymphocytesBreast NeoplasmsFemaleHumansImmunoglobulin AImmunoglobulin GLymphocytes, Tumor-InfiltratingMiddle AgedAntigens, NeoplasmAutoantibodiesImmunoglobulin AImmunoglobulin Gautoantibodiesbreast cancerIgAIgGtertiary lymphoid structurestumor-infiltrating B cells

Identifiers

PMID30515157
PMCPMC6255822
OpenAlexW2900657509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.