ReviewFrontiers in microbiology2018
Sublethal Injury and Viable but Non-culturable (VBNC) State in Microorganisms During Preservation of Food and Biological Materials by Non-thermal Processes.
Review in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed.
- Combined High Hydrostatic Pressure and Additive Chemical Treatment Enhances Decontamination Efficiency in Bone Tissue Infected with Staphylococcal Biofilms.Microorganisms · 2026Article
- Differential Induction and Resuscitation of the Viable but Non-Culturable (VBNC) State inMicroorganisms · 2026Article
- Growth phase-specific induction of a viable but nonculturable (VBNC) state inMicrobiology spectrum · 2026Article
- Challenge Test Analysis ofFoods (Basel, Switzerland) · 2026Article
- Stress-Driven Tolerance and Persistence ofBiology · 2026Review
- Establishing a Rapid Enrichment Medium forFoods (Basel, Switzerland) · 2026Article
- Dormancy in Non-Spore-Forming Bacteria: A Review.Microorganisms · 2025Review
- Probiotic Viability Reconsidered: Integrating VBNC Resuscitation and Culture-Independent Methods for Accurate Probiotic Enumeration.Microorganisms · 2025Review
- The Effect of Non-Thermal Processing on the Fate of Pathogenic Bacteria and Hidden Hazardous Risks.Foods (Basel, Switzerland) · 2025Review
- Application of Chitosan-Based Active Packaging with Rice Bran Extract in Combination with High Hydrostatic Pressure in the Preservation of Sliced Dry-Cured Iberian Ham.Gels (Basel, Switzerland) · 2025Article
- How Long Do Microorganisms Survive and Persist in Food? A Systematic Review.Microorganisms · 2025Review
- Viable but non-cultivable state in oral microbiota: a critical review of an underexplored microbial survival strategy.Frontiers in cellular and infection microbiology · 2025Review
- Improvement of Selected Quality and Safety Traits in Turmeric-Enriched Kale Pesto Using Blue Light and Sous-Vide.Molecules (Basel, Switzerland) · 2024Article
- Sublethal injury and recovery of Escherichia coli O157:H7 after dielectric barrier discharge plasma treatment.Archives of microbiology · 2024Article
- Investigating the Antibacterial Effect of a Novel Gallic Acid-Based Green Sanitizer Formulation.Foods (Basel, Switzerland) · 2024Article
- Antibacterial Effects of Thermosonication Technology onFoods (Basel, Switzerland) · 2024Article
- Sublethal Damage Caused by Cold Plasma onFoods (Basel, Switzerland) · 2024Article
- The Novel Concept of Synergically Combining: High Hydrostatic Pressure and Lytic Bacteriophages to Eliminate Vegetative and Spore-Forming Bacteria in Food Products.Foods (Basel, Switzerland) · 2024Review
- Microgreens and novel non-thermal seed germination techniques for sustainable food systems: a review.Food science and biotechnology · 2024Review
- Deep Impact: Shifts of Native Cultivable Microbial Communities on Fresh Lettuce after Treatment with Plasma-Treated Water.Foods (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The viable but non-culturable (VBNC) state, as well as sublethal injury of microorganisms pose a distinct threat to food safety, as the use of traditional, culture-based microbiological analyses might lead to an underestimation or a misinterpretation of the product's microbial status and recovery phenomena of microorganisms may occur. For thermal treatments, a large amount of data and experience is available and processes are designed accordingly. In case of innovative inactivation treatments, however, there are still several open points with relevance for the investigation of inactivation mechanisms as well as for the application and validation of the preservation processes. Thus, this paper presents a comprehensive compilation of non-thermal preservation technologies, i.e., high hydrostatic pressure (HHP), pulsed electric fields (PEFs), pulsed light (PL), and ultraviolet (UV) radiation, as well as cold plasma (CP) treatments. The basic technological principles and the cellular and molecular mechanisms of action are described. Based on this, appropriate analytical methods are outlined, i.e., direct viable count, staining, and molecular biological methods, in order to enable the differentiation between viable and dead cells, as well as the possible occurrence of an intermediate state. Finally, further research needs are outlined.
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Registered trials
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