Evidence map›Paper›PMID 30515136›Full record

ArticleFrontiers in microbiology2018

The MtrCDE Efflux Pump Contributes to Survival of

Jonathan W Handing, Stephanie A Ragland, Urmila V Bharathan, Alison K Criss

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. The frequency of mutations in theFrontiers in microbiology · 2024
    Pooled it
  2. An antibody-drug conjugate active against antibiotic-resistantProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Review
  4. Article
  5. Frontiers in microbiology · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Clinical microbiology reviews · 2024
    Review
  14. Article
  15. Article
  16. Review
  17. Immune responses toFrontiers in immunology · 2023
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jonathan W HandingDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, United States.
Stephanie A RaglandDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, United States.
Urmila V BharathanDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, United States.
Alison K CrissDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, United States.
University of Virginia · US

Funding

INFECTIOUS DISEASES TRAINING PROGRAMT32AI007046 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Alison K Criss, William A Petri · 1985 to 2026
$15.3M
Survival of Neisseria gonorrhoeae after primary human neutrophil challengeR01AI097312 · NIAID · UNIVERSITY OF VIRGINIA · PI CRISS, ALISON K · 2012 to 2022
$4.6M
Survival of Neisseria gonorrhoeae after primary human neutrophil challengeR37AI097312 · NIAID · UNIVERSITY OF VIRGINIA · PI Alison K Criss · 2025 to 2026
$1.1M
NIAID NIH HHS R01 AI097312NIAID NIH HHS R37 AI097312NIAID NIH HHS T32 AI007046
6 · The paper itself

Abstract

The mucosal inflammatory response to

Indexed as

antimicrobial peptideefflux pumpgranuleNeisseria gonorrhoeaeneutrophilneutrophil extracellular trap

Identifiers

PMID30515136
PMCPMC6256084
OpenAlexW2898220215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.