ArticleEmerging microbes & infections2018
A viral race for primacy: co-infection of a natural pair of low and highly pathogenic H7N7 avian influenza viruses in chickens and embryonated chicken eggs.
Article in Emerging microbes & infections, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Transmission Pathways of Zoonotic Influenza Viruses and Influencing Factors: A Systematic Review of Recent Findings.Viruses · 2025Pooled it
- Pooled it
- Ecology of Low Pathogenicity Avian Influenza Virus H7 in Wild Birds in South-Eastern Australia Prior to Emergence of High Pathogenicity Avian Influenza H7 in Poultry.Influenza and other respiratory viruses · 2026Article
- Host genetics, lung T-cell immunity, and laying activity determine the disease outcome in avian influenza virus-infected chickens.Veterinary research · 2026Article
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- Article
- Dominant HPAIV H5N1 genotypes of Germany 2021/2022 are linked to high virulence in Pekin ducklings.Npj viruses · 2024Article
- High pathogenicity avian influenza virus emergence: Blame it on chickens or on humans raising chickens?PLoS pathogens · 2024Article
- Outcome of H5N1 clade 2.3.4.4b virus infection in calves and lactating cows.bioRxiv : the preprint server for biology · 2024Article
- Automated quantification of avian influenza virus antigen in different organs.Scientific reports · 2024Article
- Species-specific emergence of H7 highly pathogenic avian influenza virus is driven by intrahost selection differences between chickens and ducks.PLoS pathogens · 2024Article
- The role of PB1-F2 in adaptation of high pathogenicity avian influenza virus H7N7 in chickens.Veterinary research · 2024Article
- Evidence for Different Virulence Determinants and Host Response after Infection of Turkeys and Chickens with Highly Pathogenic H7N1 Avian Influenza Virus.Journal of virology · 2022Article
- Opposite Outcomes of the Within-Host Competition between High- and Low-Pathogenic H5N8 Avian Influenza Viruses in Chickens Compared to Ducks.Journal of virology · 2022Article
- The role of glycosylation in the N-terminus of the hemagglutinin of a unique H4N2 with a natural polybasic cleavage site in virus fitnessVirulence · 2021Article
- From one to many: The within-host rise of viral variants.PLoS pathogens · 2021Article
- Egyptian Fruit Bats (Viruses · 2021Article
- Neuraminidase-associated plasminogen recruitment enables systemic spread of natural avian Influenza viruses H3N1.PLoS pathogens · 2021Article
- H7N7 Avian Influenza Virus Mutation from Low to High Pathogenicity on a Layer Chicken Farm in the UK.Viruses · 2021Article
- Non-basic amino acids in the hemagglutinin proteolytic cleavage site of a European H9N2 avian influenza virus modulate virulence in turkeys.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Highly pathogenic avian influenza virus (HPAIV) infection in poultry caused devastating mortality and economic losses. HPAIV of subtypes H5 and H7 emerge from precursor viruses of low pathogenicity (LP) by spontaneous mutation associated with a shift in the susceptibility of the endoproteolytic cleavage site of the viral hemagglutinin protein from trypsin- to furin-like proteases. A recently described natural pair of LP/HP H7N7 viruses derived from two spatio-temporally linked outbreaks in layer chickens was used to study how a minority of mutated HP virions after de novo generation in a single host might gain primacy. Co-infection experiments in embryonated eggs and in chickens were conducted to investigate amplification, spread and transmissionof HPAIV within a poultry population that experiences concurrent infection by an antigenically identical LP precursor virus. Simultaneous LPAIV co-infection (inoculum dose of 10
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.