Evidence map›Paper›PMID 30514882›Full record

ArticleScientific reports2018

PECAM/eGFP transgenic mice for monitoring of angiogenesis in health and disease.

Florian Winkler, Katia Herz, Sarah Rieck, Kenichi Kimura, Tianyuan Hu, Wilhelm Röll, Michael Hesse, Bernd K Fleischmann, Daniela Wenzel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Florian WinklerInstitute of Physiology I, Life&Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Katia HerzInstitute of Physiology I, Life&Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Sarah RieckInstitute of Physiology I, Life&Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Kenichi KimuraInstitute of Physiology I, Life&Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Tianyuan HuInstitute of Physiology I, Life&Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Wilhelm RöllDepartment of Cardiac Surgery, Medical Faculty, University of Bonn, Bonn, Germany.
Michael HesseInstitute of Physiology I, Life&Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Bernd K FleischmannInstitute of Physiology I, Life&Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Daniela WenzelInstitute of Physiology I, Life&Brain Center, Medical Faculty, University of Bonn, Bonn, Germany. dwenzel@uni-bonn.de.
Life & Brain (Germany) · DEUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the monitoring of vascular growth as well as adaptive or therapeutic (re)vascularization endothelial-specific reporter mouse models are valuable tools. However, currently available mouse models have limitations, because not all endothelial cells express the reporter in all developmental stages. We have generated PECAM/eGFP embryonic stem (ES) cell and mouse lines where the reporter gene labels PECAM

Indexed as

Models, AnimalNeovascularization, PathologicNeovascularization, PhysiologicAnimalsBone MarrowCell LineEndothelial CellsEndothelium, VascularGenes, ReporterGreen Fluorescent ProteinsMiceMice, TransgenicMouse Embryonic Stem CellsPlatelet Endothelial Cell Adhesion Molecule-1Vascular RemodelingGreen Fluorescent ProteinsPecam1 protein, mousePlatelet Endothelial Cell Adhesion Molecule-1

Identifiers

PMID30514882
PMCPMC6279819
OpenAlexW2902579829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.