Evidence map›Paper›PMID 30514817›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Isolation and characterization of adrenocortical progenitors involved in the adaptation to stress.

Charlotte Steenblock, Maria F Rubin de Celis, Luis F Delgadillo Silva, Verena Pawolski, Ana Brennand, Martin Werdermann, Ilona Berger, Alice Santambrogio, Mirko Peitzsch, Cynthia L Andoniadou and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Approach to the Child and Adolescent With Adrenal Insufficiency.The Journal of clinical endocrinology and metabolism · 2025
    Review
  6. Review
  7. Thromboxane AAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Isolation andSTAR protocols · 2021
    Article
  12. Article
  13. Article
  14. Review
  15. Adrenal cortex renewal in health and disease.Nature reviews. Endocrinology · 2021
    Review
  16. The Sexually Dimorphic Adrenal Cortex: Implications for Adrenal Disease.International journal of molecular sciences · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. New Horizons: Novel Adrenal Regenerative Therapies.The Journal of clinical endocrinology and metabolism · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Charlotte SteenblockDepartment of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Maria F Rubin de CelisDepartment of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Luis F Delgadillo SilvaDFG Center for Regenerative Therapies Dresden, Technische Universität Dresden, 01307 Dresden, Germany.
Verena PawolskiDepartment of Anatomy, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Ana BrennandDepartment of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Martin WerdermannDepartment of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Ilona BergerDepartment of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Alice SantambrogioDepartment of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Mirko PeitzschInstitute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
Cynthia L AndoniadouDepartment of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.ORCID 0000-0003-4311-5855
Andrew V SchallyDivision of Endocrinology, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136; andrew.schally@va.gov stefan.bornstein@uniklinikum-dresden.de.
Stefan R BornsteinDepartment of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany; andrew.schally@va.gov stefan.bornstein@uniklinikum-dresden.de.
King's College London · GBUniversity Hospital Carl Gustav Carus · DETechnische Universität Dresden · DEUniversity of Miami · US

Funding

Medical Research Council MR/L016729/1
6 · The paper itself

Abstract

The adrenal gland is a master regulator of the human body during response to stress. This organ shows constant replacement of senescent cells by newly differentiated cells. A high degree of plasticity is critical to sustain homeostasis under different physiological demands. This is achieved in part through proliferation and differentiation of adult adrenal progenitors. Here, we report the isolation and characterization of a Nestin

Indexed as

Adaptation, PhysiologicalHomeostasisStress, PhysiologicalAdrenal CortexAdrenocorticotropic HormoneAnimalsCell DifferentiationCells, CulturedMiceStem CellsAdrenocorticotropic Hormoneadrenalcortexprogenitorsstem cellsstress

Identifiers

PMID30514817
PMCPMC6304967
OpenAlexW2902424823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.