Evidence map›Paper›PMID 30514801›Full record

ArticleHaematologica2019

T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development.

Charles E de Bock, Michelle Down, Kinsha Baidya, Bram Sweron, Andrew W Boyd, Mark Fiers, Gordon F Burns, Timothy J Molloy, Richard B Lock, Jean Soulier and 5 more

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. FAT1 Gene Expression in Iranian Acute Lymphoid and Myeloid Leukemia Patients.International journal of hematology-oncology and stem cell research · 2023
    Article
  4. Article
  5. Article
  6. Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 4 countries.

Charles E de BockKU Leuven, Center for Human Genetics, Belgium Rick.Thorne@newcastle.edu.au cdebock@ccia.org.au.
Michelle DownLeukaemia Foundation Laboratory, QIMR-Berghofer Medical Research Institute, Brisbane, Australia.
Kinsha BaidyaSchool of Medical Sciences and Prince of Wales Clinical School, University of New South Wales, Sydney, Australia.
Bram SweronKU Leuven, Center for Human Genetics, Belgium.
Andrew W BoydLeukaemia Foundation Laboratory, QIMR-Berghofer Medical Research Institute, Brisbane, Australia.
Mark FiersVIB-KU Leuven Center for Brain & Disease Research, Belgium.
Gordon F BurnsCancer Research Unit, The University of Newcastle, Callaghan, NSW, Australia.
Timothy J MolloySt Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia.
Richard B LockChildren's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, Australia.
Jean SoulierU944 INSERM and Hematology laboratory, St-Louis Hospital, APHP, Hematology University Institute, University Paris-Diderot, France.
Tom TaghonDepartment of Diagnostic Sciences, Faculty of Medicine and Health Sciences, Ghent University, Belgium.
Pieter Van VlierbergheCenter for Medical Genetics, Ghent University Hospital, Belgium Cancer Research Institute Ghent (CRIG), Belgium.
Jan CoolsKU Leuven, Center for Human Genetics, Belgium.
Jeff HolstTranslational Cancer Metabolism Laboratory, Lowy Cancer Research Centre, University of New South Wales, Sydney, Australia.
Rick F ThorneTranslational Research Institute, Henan Provincial People's Hospital, School of Medicine, Henan University, Zhengzhou, China Rick.Thorne@newcastle.edu.au cdebock@ccia.org.au.
UNSW Sydney · AUVIB-KU Leuven Center for Cancer Biology · BEAssistance Publique – Hôpitaux de Paris · FRGhent University · BEGhent University Hospital · BEHenan Provincial People's Hospital · CNLeukaemia Foundation of Queensland · AUQIMR Berghofer Medical Research Institute · AUUniversity of Newcastle Australia · AUVIB-KU Leuven Center for Brain & Disease Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, LeukemicMutationCadherinsHumansPrecursor T-Cell Lymphoblastic Leukemia-LymphomaProtein IsoformsReceptor, Notch1T-LymphocytesTumor Cells, CulturedCadherinsFAT1 protein, humanNOTCH1 protein, humanProtein IsoformsReceptor, Notch1

Identifiers

PMID30514801
PMCPMC6518915
OpenAlexW2902627440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.