Evidence map›Paper›PMID 30514797›Full record

ArticleHaematologica2019

Kinase activity is impaired in neutrophils of sepsis patients.

Arie J Hoogendijk, Lonneke A van Vught, Maryse A Wiewel, Gwenny M Fuhler, Hakima Belkasim-Bohoudi, Janneke Horn, Marcus J Schultz, Brendon P Scicluna, Maikel P Peppelenbosch, Cornelis van 't Veer and 2 more

Open access · goldAbstract readLetter
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Drug Discovery in Liver Disease Using Kinome Profiling.International journal of molecular sciences · 2021
    Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Arie J HoogendijkCenter for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam.
Lonneke A van VughtCenter for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam.
Maryse A WiewelCenter for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam.
Gwenny M FuhlerDepartment of Gastroenterology and Hepatology, Erasmus MC, Erasmus University of Rotterdam.
Hakima Belkasim-BohoudiCenter for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam.
Janneke HornDepartment of Intensive Care, Academic Medical Center, University of Amsterdam.
Marcus J SchultzDepartment of Intensive Care, Academic Medical Center, University of Amsterdam.
Brendon P SciclunaCenter for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam.
Maikel P PeppelenboschDepartment of Gastroenterology and Hepatology, Erasmus MC, Erasmus University of Rotterdam.
Cornelis van 't VeerCenter for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam.
Alex F de VosCenter for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam.
Tom van der PollCenter for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam t.vanderpoll@amc.uva.nl.
University of Amsterdam · NLAcademic Medical Center · NLErasmus MC · NLErasmus University Rotterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkersEnzyme ActivationHumansNeutrophilsPhosphorylationPhosphotransferasesProteomeProteomicsSepsisBiomarkersPhosphotransferasesProteome

Identifiers

PMID30514797
PMCPMC6545843
OpenAlexW2903127095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.