ArticleThe Veterinary record2019
Cats with IRIS stage 1 and 2 chronic kidney disease maintain body weight and lean muscle mass when fed food having increased caloric density, and enhanced concentrations of carnitine and essential amino acids.
Article in The Veterinary record, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Muscle Mass Is a Better Predictor of Survival in Dogs With Chronic Kidney Disease Compared to Body Condition Score.Journal of animal physiology and animal nutrition · 2026Article
- A Real-World Data Analysis on Feline Chronic Kidney Disease in Greece: Clinical Profiles, Comorbidities, and Quality of Life.Veterinary sciences · 2026Article
- Does the definition of human ultra-processed foods apply to dog and cat foods? A review of pet food processing techniques, their impact on health, and a call for pet food processing classification.Frontiers in veterinary science · 2026Article
- Epidemiology of Chronic Kidney Disease (CKD) in Cats: An Analysis of the Factors Involved.Life (Basel, Switzerland) · 2025Article
- Caregivers' perspectives on feline chronic kidney disease in Portugal: a questionnaire-based study.Journal of feline medicine and surgery · 2025Article
- The clinical efficacy of cGMP-specific sildenafil on mitochondrial biogenesis induction and renal damage in cats with acute on chronic kidney disease.BMC veterinary research · 2024Article
- Untargeted metabolomic profiling of serum from client-owned cats with early and late-stage chronic kidney disease.Scientific reports · 2024Article
- Dietary choline, but not L-carnitine, increases circulating lipid and lipoprotein concentrations, without affecting body composition, energy expenditure or respiratory quotient in lean and obese male cats during weight maintenance.Frontiers in veterinary science · 2023Article
- Article
- Ionized hypercalcemia in cats with azotemic chronic kidney disease (2012-2018).Journal of veterinary internal medicine · 2022Article
- Serum and Fecal Amino Acid Profiles in Cats with Chronic Kidney Disease.Veterinary sciences · 2022Article
- Dietary Carnitine and Carnosine Increase Body Lean in Healthy Cats in a Preliminary Study.Biology · 2021Article
- Chemokine Therapy in Cats With Experimental Renal Fibrosis and in a Kidney Disease Pilot Study.Frontiers in veterinary science · 2021Article
- Cats Have Increased Protein Digestibility as Compared to Dogs and Improve Their Ability to Absorb Protein as Dietary Protein Intake Shifts from Animal to Plant Sources.Animals : an open access journal from MDPI · 2020Article
- Chronic kidney disease in cats alters response of the plasma metabolome and fecal microbiome to dietary fiber.PloS one · 2020Article
- Usefulness of Urinary Creatinine/Urea Nitrogen Ratio as Indicator of Body Protein Catabolism in Dogs Fed Low Protein Diets.Frontiers in veterinary science · 2019Article
- Metabolic Alterations Associated With Rapidly Progressive Chronic Kidney Disease in Cats.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A prospective, randomised, 6-month feeding trial was performed in 28 adult cats with International Renal Interest Society (IRIS) stage 1 and 2 chronic kidney disease (CKD). All cats were assigned to either a control food: Royal Canin Renal Support A Feline, dry or a test food: Hill's Prescription Diet k/d Feline with chicken, dry. Food intake was recorded daily; body weight weekly; and serum, urine, dual-energy x-ray absorptiometry (DEXA) and body condition assessments were performed at 0, 1, 3 and 6 months. Twenty cats (9 control, 11 test group) completed the study according to protocol. Cats consuming control food had significant loss of body weight (n=14; mean, -13.0 per cent, P<0.0001) and lean body mass (LBM; mean, -11.1 per cent, P<0.0001) over the 6-month feeding period, whereas cats consuming test food had a significant increase in body weight (n=14; mean, 5.8 per cent, P=0.003) and no change in LBM (P=0.42). Cats consumed 23 per cent more calories (P=0.05) when fed test food (mean, 207.1 kcal/day) compared with cats fed control food (mean, 168.0 kcal/day). Serum creatinine increased at a faster rate (P=0.0004) in cats consuming control food compared with cats consuming test food. Cats consuming test food had increased caloric and essential amino acid intake, increased body weight, stable biomarkers of kidney function and maintained LBM compared with cats consuming control food.
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