Evidence map›Paper›PMID 30514409›Full record

ArticlePsychological medicine2019

Risk of schizophrenia, schizoaffective, and bipolar disorders by migrant status, region of origin, and age-at-migration: a national cohort study of 1.8 million people.

Jennifer Dykxhoorn, Anna-Clara Hollander, Glyn Lewis, Cecelia Magnusson, Christina Dalman, James B Kirkbride

Abstract read
In one paragraph

Article in Psychological medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Migration and schizophrenia: meta-analysis and explanatory framework.European archives of psychiatry and clinical neuroscience · 2020
    Pooled it
  2. Article
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  6. Article
  7. Schizophrenia.Nature reviews. Disease primers · 2025
    Review
  8. Article
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  13. The social determinants of mental health and disorder: evidence, prevention and recommendations.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jennifer DykxhoornDivision of Psychiatry, UCL, London, UK.ORCID 0000-0001-6391-8626
Anna-Clara HollanderDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Glyn LewisDivision of Psychiatry, UCL, London, UK.
Cecelia MagnussonDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Christina DalmanDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
James B KirkbrideDivision of Psychiatry, UCL, London, UK.

Funding

Department of HealthWellcome Trust
6 · The paper itself

Abstract

backgroundWe assessed whether the risk of various psychotic disorders and non-psychotic bipolar disorder (including mania) varied by migrant status, a region of origin, or age-at-migration, hypothesizing that risk would only be elevated for psychotic disorders.

methodsWe established a prospective cohort of 1 796 257 Swedish residents born between 1982 and 1996, followed from their 15th birthday, or immigration to Sweden after age 15, until diagnosis, emigration, death, or end of 2011. Cox proportional hazards models were used to model hazard ratios by migration-related factors, adjusted for covariates.

resultsAll psychotic disorders were elevated among migrants and their children compared with Swedish-born individuals, including schizophrenia and schizoaffective disorder (adjusted hazard ratio [aHR]migrants: 2.20, 95% CI 1.96-2.47; aHRchildren : 2.00, 95% CI 1.79-2.25), affective psychotic disorders (aHRmigrant1.42, 95% CI 1.25-1.63; aHRchildren: 1.22 95% CI 1.07-1.40), and other non-affective psychotic disorders (aHRmigrant: 1.97, 95% CI 1.81-2.14; aHRchildren: 1.68, 95% CI 1.54-1.83). For all psychotic disorders, risks were generally highest in migrants from Africa (i.e. aHRschizophrenia: 5.24, 95% CI 4.26-6.45) and elevated at most ages-of-migration. By contrast, risk of non-psychotic bipolar disorders was lower for migrants (aHR: 0.58, 95% CI 0.52-0.64) overall, and across all ages-of-migration except infancy (aHR: 1.20; 95% CI 1.01-1.42), while risk for their children was similar to the Swedish-born population (aHR: 1.00, 95% CI 0.93-1.08).

conclusionsIncreased risk of psychiatric disorders associated with migration and minority status may be specific to psychotic disorders, with exact risk dependent on the region of origin.

Indexed as

AdolescentAdultAgedAge FactorsBipolar DisorderFemaleHumansMaleMiddle AgedProportional Hazards ModelsProspective StudiesPsychotic DisordersRegistriesRisk FactorsSchizophreniaSwedenBipolar disorderepidemiologymaniamigrationpsychotic disordersschizophrenia

Identifiers

PMID30514409
PMCPMC6763532

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.