Evidence map›Paper›PMID 30514106›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.

Giovanna Sociali, Alessia Grozio, Irene Caffa, Susanne Schuster, Pamela Becherini, Patrizia Damonte, Laura Sturla, Chiara Fresia, Mario Passalacqua, Francesca Mazzola and 6 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05684367 (Center-Based and Home-Based Walking Exercise Intervention to Reduce Fatigue in Older Breast Cancer Survivors), which is not on this map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05684367 narecruitingnot on this mapstarted 2023, after this paper: background citation

Center-Based and Home-Based Walking Exercise Intervention to Reduce Fatigue in Older Breast Cancer Survivors

TypeinterventionalSponsorUniversity of FloridaRan2023 to 2026Enrolled24ConditionsFatigue, Breast Cancer, Cancer, Therapy-RelatedArmsCenter-Based Walking Exercise, Home-Based Walking Exercise
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 65 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Interplay Between the Circadian Clock and Sirtuins.International journal of molecular sciences · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Subcellular one carbon metabolism in cancer, aging and epigenetics.Frontiers in epigenetics and epigenomics · 2024
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Nicotine rebalances NADNature communications · 2023
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Giovanna SocialiSection of Biochemistry, Department of Experimental Medicine, Center for Excellence in Biomedical Research (CEBR), University of Genoa, Genoa, Italy.
Alessia GrozioSection of Biochemistry, Department of Experimental Medicine, Center for Excellence in Biomedical Research (CEBR), University of Genoa, Genoa, Italy.
Irene CaffaDepartment of Internal Medicine, University of Genoa, Genoa, Italy.
Susanne SchusterCenter for Pediatric Research Leipzig (CPL), University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.
Pamela BecheriniDepartment of Internal Medicine, University of Genoa, Genoa, Italy.
Patrizia DamonteDepartment of Internal Medicine, University of Genoa, Genoa, Italy.
Laura SturlaSection of Biochemistry, Department of Experimental Medicine, Center for Excellence in Biomedical Research (CEBR), University of Genoa, Genoa, Italy.
Chiara FresiaSection of Biochemistry, Department of Experimental Medicine, Center for Excellence in Biomedical Research (CEBR), University of Genoa, Genoa, Italy.
Mario PassalacquaSection of Biochemistry, Department of Experimental Medicine, Center for Excellence in Biomedical Research (CEBR), University of Genoa, Genoa, Italy.
Francesca MazzolaDepartment of Clinical Sciences, Polytechnic University of Marche, Ancona, Italy.
Nadia RaffaelliDepartment of Agricultural, Food, and Environmental Sciences, Polytechnic University of Marche, Ancona, Italy.
Antje GartenCenter for Pediatric Research Leipzig (CPL), University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.
Wieland KiessCenter for Pediatric Research Leipzig (CPL), University Hospital for Children and Adolescents, University of Leipzig, Leipzig, Germany.
Michele CeaDepartment of Internal Medicine, University of Genoa, Genoa, Italy.
Alessio NencioniDepartment of Internal Medicine, University of Genoa, Genoa, Italy.
Santina BruzzoneSection of Biochemistry, Department of Experimental Medicine, Center for Excellence in Biomedical Research (CEBR), University of Genoa, Genoa, Italy.
University of Genoa · ITMarche Polytechnic University · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in the NAD

Indexed as

Cell LineCell Line, TumorCytokinesDoxorubicinGlucosephosphate DehydrogenaseHEK293 CellsHep G2 CellsHumansHydrogen PeroxideMCF-7 CellsNADPNeoplasmsNicotinamide PhosphoribosyltransferaseOxidative StressPoly(ADP-ribose) PolymerasesSirtuinsCytokinesDoxorubicinGlucosephosphate DehydrogenaseHydrogen PeroxideNADPNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, humanPoly(ADP-ribose) PolymerasesSIRT6 protein, humanSirtuinsnicotinamide adenine dinucleotidenicotinamide phosphoribosyltransferaseSirtuin 6

Identifiers

PMID30514106
PMCPMC6988859
OpenAlexW2902767785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.