ReviewJournal of neurosurgical sciences2019
Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome.
Review in Journal of neurosurgical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 43 citations in OpenAlex.
- Epigenetic Regulation of the NET Formation-Blood-Brain Barrier Axis in Ischemic Stroke: Mechanisms, Therapeutic Targets and Translational Perspectives.Neurology international · 2026Review
- Dual-energy computed tomography venography parameters as potential indicators for pulmonary embolism in deep vein thrombosis.Journal of thoracic disease · 2026Article
- Widened arterial time-density curves of CTP may identify cardioembolic etiology in acute large-artery occlusion stroke.Neuroradiology · 2026Article
- Experimental Characterisation of Differently Composed Thrombus Entities with Spectral-Detector-CT.Neurology international · 2026Article
- Clot Composition and Ischemic Stroke Etiology: A Contemporary Narrative Review.Journal of clinical medicine · 2025Review
- Characterizing Stroke Clots Using Single-Cell Sequencing.Journal of the American Heart Association · 2025Article
- Identification of Differential Proteins in Thrombi of Cardioembolic and Atherothrombotic Etiology in Patients with Ischemic Stroke.International journal of molecular sciences · 2025Article
- Thrombus perviousness in acute ischemic stroke: a scoping review of methodology, predictive value, and future perspectives.Neuroradiology · 2025Article
- Unraveling the Enigma: Correlating Thrombus Histopathology With the Number of Passes in Mechanical Thrombectomy.Cureus · 2025Article
- Thrombus migration in intracranial large vessel occlusion: course, predictors, and impact on endovascular thrombectomy.Frontiers in neurology · 2025Article
- Histopathological composition of thrombus material in a large cohort of patients with acute ischemic stroke: a study of atypical clots.Frontiers in neurology · 2025Article
- Effect of MR-guided perfusion imaging mismatch profiles within 6 h on endovascular thrombectomy outcomes.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Dynamic Perviousness Has Predictive Value for Clot Fibrin Content in Acute Ischemic Stroke.Diagnostics (Basel, Switzerland) · 2024Article
- Dynamic Perviousness Predicts Revascularization Success in Acute Ischemic Stroke.Diagnostics (Basel, Switzerland) · 2024Article
- What is a Challenging Clot? : A DELPHI Consensus Statement from the CLOTS 7.0 Summit.Clinical neuroradiology · 2023Article
- Advancing Stroke Research on Cerebral Thrombi with Omic Technologies.International journal of molecular sciences · 2023Review
- Clot Morphology in Acute Ischemic Stroke Decision Making.International journal of molecular sciences · 2022Review
- Magnetic resonance imaging quantitative T2* mapping to predict the red blood cell content of in vivo thrombi retrieved from patients with large vessel occlusions in acute ischemic stroke.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022Article
- Histology of Cerebral Clots in Cryptogenic Stroke Varies According to the Presence of a Patent Foramen Ovale.International journal of molecular sciences · 2022Article
- Quantitative Assessment of Hyperdense Sign Measured by Hounsfield Units is Associated with Unsuccessful Mechanical Thrombectomy.Clinical neuroradiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Mechanical thrombectomy has become the stand of care for patients with large vessel occlusions, yet major improvements in thrombectomy speed, efficacy, and completeness can still be achieved. High rates of clot fragmentation and failure to remove the clot resulting in poor neurological outcomes suggest that in order to further advance the field of stroke intervention we must turn our attention towards understanding the science of clot. Accurately identifying the composition of the occlusive clot prior to intervention could significantly influence the success of the revascularization strategy used to treat them. Numerous features of thromboemboli could be studied and characterized, including quantitative histomorphometry and diagnostic imaging characteristics. Each of these features might logically predict superior thrombectomy outcomes with one device or another. This article aims to review the current literature on histopathological composition of acute ischemic stroke clots, with a particular focus on the correlation between clot composition and diagnostic imaging, stroke etiology and revascularization outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.