Evidence map›Paper›PMID 30514058›Full record

ArticleJournal of preventive medicine and public health = Yebang Uihakhoe chi2018

The Risk of Colorectal Cancer After Cholecystectomy or Appendectomy: A Population-based Cohort Study in Korea.

Joonki Lee, Sunho Choe, Ji Won Park, Seung-Yong Jeong, Aesun Shin

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of preventive medicine and public health = Yebang Uihakhoe chi, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Joonki LeeDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Sunho ChoeDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Ji Won ParkDivision of Colorectal Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Seung-Yong JeongDivision of Colorectal Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Aesun ShinDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Seoul National University · KR

Funding

Seoul National University College of Medicine 800-20170161
6 · The paper itself

Abstract

objectivesWe investigated the association between cholecystectomy or appendectomy and the subsequent risk of colorectal cancer (CRC) in the Korean population.

methodsA retrospective cohort study was conducted with the National Health Insurance Service-National Sample Cohort of Korea; this sample was followed up from January 1, 2002, until the date of CRC incidence, loss to follow-up, or December 31, 2015. The exposure status of cholecystectomy and appendectomy was treated as a time-varying covariate. The calculated risk of CRC was stratified by follow-up period, and the association between these surgical procedures and CRC was investigated by a Cox regression model applying appropriate lag periods.

resultsA total of 707 663 individuals were identified for analysis. The study population was followed up for an average of 13.66 years, and 4324 CRC cases were identified. The hazard ratio (HR) of CRC was elevated in the first year after cholecystectomy (HR, 1.71; 95% confidence interval [CI], 1.01 to 2.89) and in the first year and 2-3 years after appendectomy (HR, 4.22; 95% CI, 2.87 to 6.20; HR, 2.34; 95% CI, 1.36 to 4.03, respectively). The HRs of CRC after applying 1 year of lag after cholecystectomy and 3 years of lag after appendectomy were 0.80 (95% CI, 0.57 to 1.13) and 0.77 (95% CI, 0.51 to 1.16), respectively.

conclusionsThe risk of CRC increased in the first year after cholecystectomy and appendectomy, implying the possibility of bias. When appropriate lag periods after surgery were applied, no association was found between cholecystectomy or appendectomy and CRC.

Indexed as

AdultAppendectomyCholecystectomyColorectal NeoplasmsFemaleHumansIncidenceMaleMiddle AgedProportional Hazards ModelsRepublic of KoreaRetrospective StudiesRiskAppendectomyCholecystectomyCohort studiesColorectal neoplasmsKorea

Identifiers

PMID30514058
PMCPMC6283741
OpenAlexW2898968442

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.