Evidence map›Paper›PMID 30513960›Full record

ArticleInternational journal of molecular sciences2018

Combined Gastric and Colorectal Cancer Screening-A New Strategy.

Michael Selgrad, Jan Bornschein, Arne Kandulski, Jochen Weigt, Albert Roessner, Thomas Wex, Peter Malfertheiner

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Screening for and surveillance of premalignant conditions of the stomach.Best practice & research. Clinical gastroenterology · 2025
    Review
  3. Article
  4. Review
  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Michael SelgradDepartment of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke-University of Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. michael.selgrad@ukr.de.ORCID 0000-0002-1876-1188
Jan BornscheinDepartment of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke-University of Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. jan.bornschein@ouh.nhs.uk.
Arne KandulskiDepartment of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke-University of Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. arne.kandulski@ukr.de.
Jochen WeigtDepartment of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke-University of Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. jochen.weigt@med.ovgu.de.
Albert RoessnerDepartment of Pathology, Otto-von-Guericke-University of Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. albert.roessner@med.ovgu.de.
Thomas WexDepartment of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke-University of Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. t.wex@schenk-ansorge.de.
Peter MalfertheinerDepartment of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke-University of Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. peter.malfertheiner@med.ovgu.de.
Otto-von-Guericke-Universität Magdeburg · DEUniversity Hospital Regensburg · DEJohn Radcliffe Hospital · GBUniversity Hospital Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur aim was to evaluate the feasibility of a serological assessment of gastric cancer risk in patients undergoing colonoscopy in countries with low-to-moderate incidence rates.

methodsSerum samples were prospectively collected from 453 patients (>50 years old) undergoing colonoscopies. Of these, 279 (61.6%) also underwent gastroscopy to correlate the results for serum pepsinogen I and II (sPG-I and sPG-II), sPG-I/II ratio, and anti-

results

conclusionsThe assessment of serum pepsinogen allows the identification of patients at increased risk of gastric cancer. A prevention strategy of combining a screening colonoscopy with a serological screening for preneoplastic gastric changes should be considered in the general population.

Indexed as

AgedAged, 80 and overColorectal NeoplasmsEarly Detection of CancerFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedPepsinogen ARisk AssessmentStomach NeoplasmsPepsinogen Agastric cancerHelicobacter pyloripepsinogenscreeningscreening colonoscopy

Identifiers

PMID30513960
PMCPMC6321419
OpenAlexW2903130161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.