Evidence map›Paper›PMID 30513863›Full record

ArticleInternational journal of molecular sciences2018

Low HIF-1α and low EGFR mRNA Expression Significantly Associate with Poor Survival in Soft Tissue Sarcoma Patients; the Proteins React Differently.

Swetlana Rot, Helge Taubert, Matthias Bache, Thomas Greither, Peter Würl, Hans-Jürgen Holzhausen, Alexander W Eckert, Dirk Vordermark, Matthias Kappler

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Swetlana RotDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. swetlana.rot@medizin.uni-halle.de.
Helge TaubertClinic of Urology and Pediatric Urology, FA University Hospital Erlangen-Nuremberg, 91054 Erlangen, Germany. Helge.Taubert@uk-erlangen.de.
Matthias BacheDepartment of Radiotherapy, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. matthias.bache@medizin.uni-halle.de.
Thomas GreitherCenter for Reproductive Medicine and Andrology, Martin Luther University, 06120 Halle (Saale), Germany. thomas.greither@medizin.uni-halle.de.ORCID 0000-0002-1888-7813
Peter WürlDepartment of General and Visceral Surgery, Hospital Dessau, 06847 Dessau-Roßlau, Germany. peter.wuerl@klinikum-dessau.de.
Hans-Jürgen HolzhausenInstitute of Pathology, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. Hans-juergen.holzhausen@medizin.uni-halle.de.
Alexander W EckertDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. alexander.eckert@uk-halle.de.
Dirk VordermarkDepartment of Radiotherapy, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. dirk.vordermark@uk-halle.de.
Matthias KapplerDepartment of Oral and Maxillofacial Plastic Surgery, Martin Luther University Halle-Wittenberg, 06120 Halle (Saale), Germany. matthias.kappler@medizin.uni-halle.de.ORCID 0000-0003-2002-0271
Martin Luther University Halle-Wittenberg · DEStädtisches Klinikum Dessau · DEUniversitätsklinikum Erlangen · DE

Funding

BMBF/NBL3 Grant Wilhelm-Roux-Program FKZ: 16/18
6 · The paper itself

Abstract

In various tumors, the hypoxia inducible factor-1α (

Indexed as

Gene Expression Regulation, NeoplasticAdolescentAdultAgedAged, 80 and overBiomarkers, TumorErbB ReceptorsFemaleHumansHypoxia-Inducible Factor 1, alpha SubunitMaleMiddle AgedMultivariate AnalysisProportional Hazards ModelsRNA, MessengerSarcomaBiomarkers, TumorEGFR protein, humanErbB ReceptorsHypoxia-Inducible Factor 1, alpha SubunitRNA, MessengerEGFRHIF1αprognosisSTS

Identifiers

PMID30513863
PMCPMC6321736
OpenAlexW2902411554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.