Evidence map›Paper›PMID 30513727›Full record

ArticleNutrients2018

Lipidomic Response to Coffee Consumption.

Alan Kuang, Iris Erlund, Christian Herder, Johan A Westerhuis, Jaakko Tuomilehto, Marilyn C Cornelis

Open access · goldAbstract readControlled Clinical Trial
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Association of coffee consumption with diabetes mellitus and gestational diabetes mellitus.International journal of cardiology. Cardiovascular risk and prevention · 2026
    Article
  2. Observational
  3. Article
  4. Article
  5. Coffee: Fuel for Your Day or Foe for Your Arteries.Antioxidants (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Targeted proteomic response to coffee consumption.European journal of nutrition · 2020
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 6 countries.

Alan KuangDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 North Lake Shore Drive, Suite 1400, Chicago, IL 60611, USA. alan.kuang@northwestern.edu.ORCID 0000-0001-7991-2835
Iris ErlundGenomics and Biomarkers Unit, National Institute for Health and Welfare, P.O. Box 30, 00271 Helsinki, Finland. iris.erlund@thl.fi.
Christian HerderInstitute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany. Christian.Herder@DDZ.UNI-DUESSELDORF.DE.ORCID 0000-0002-2050-093X
Johan A WesterhuisBiosystems Data Analysis, Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands. j.a.westerhuis@uva.nl.ORCID 0000-0002-6747-9779
Jaakko TuomilehtoDisease Risk Unit, National Institute for Health and Welfare, 00271 Helsinki, Finland. jaakko.tuomilehto@thl.fi.
Marilyn C CornelisDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 North Lake Shore Drive, Suite 1400, Chicago, IL 60611, USA. marilyn.cornelis@northwestern.edu.
Northwestern University · USDeutsches Diabetes-Zentrum e.V. · DEFinnish Institute for Health and Welfare · FINorth-West University · ZAUniversity of Helsinki · FI

Funding

American Diabetes Association 7-13-JF-15
6 · The paper itself

Abstract

Coffee is widely consumed and contains many bioactive compounds, any of which may impact pathways related to disease development. Our objective was to identify individual lipid changes in response to coffee drinking. We profiled the lipidome of fasting serum samples collected from a previously reported single blinded, three-stage clinical trial. Forty-seven habitual coffee consumers refrained from drinking coffee for 1 month, consumed 4 cups of coffee/day in the second month and 8 cups/day in the third month. Samples collected after each coffee stage were subject to quantitative lipidomic profiling using ion-mobility spectrometry⁻mass spectrometry. A total of 853 lipid species mapping to 14 lipid classes were included for univariate analysis. Three lysophosphatidylcholine (LPC) species including LPC (20:4), LPC (22:1) and LPC (22:2), significantly decreased after coffee intake (

Indexed as

CoffeaCoffeeDietAdultCaffeineCholesterol EstersDrinkingFatty Acids, NonesterifiedGlycerophospholipidsHumansLipid MetabolismLysophosphatidylcholinesMass SpectrometryPhosphatidylcholinesPlant PreparationsTriglyceridesCaffeineCholesterol EstersCoffeeFatty Acids, NonesterifiedGlycerophospholipidsLysophosphatidylcholinesPhosphatidylcholinesPlant PreparationsTriglyceridesbiomarkerscaffeinecoffeelipidomicslipidslysophosphatidylcholinetrial

Identifiers

PMID30513727
PMCPMC6315510
OpenAlexW2903208983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.