Evidence map›Paper›PMID 30513714›Full record

ArticleNutrients2018

Selenium Status Is Not Associated with Cognitive Performance: A Cross-Sectional Study in 154 Older Australian Adults.

Barbara R Cardoso, Ewa A Szymlek-Gay, Blaine R Roberts, Melissa Formica, Jenny Gianoudis, Stella O'Connell, Caryl A Nowson, Robin M Daly

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Ferroptotic neurodegeneration and diet: a narrative review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
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  8. Effects of Regular Brazil Nut (Foods (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Barbara R CardosoInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, 3220 Geelong, Australia. barbara.r@deakin.edu.au.ORCID 0000-0002-6393-1377
Ewa A Szymlek-GayInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, 3220 Geelong, Australia. ewa.szymlekgay@deakin.edu.au.ORCID 0000-0002-6533-7945
Blaine R RobertsThe Florey Institute of Neuroscience and Mental Health, Melbourne Dementia Research Centre, Parkville, 3050 Victoria, Australia. blaine.roberts@florey.edu.au.ORCID 0000-0001-5466-0053
Melissa FormicaInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, 3220 Geelong, Australia. mprosser@deakin.edu.au.
Jenny GianoudisInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, 3220 Geelong, Australia. j.gianoudis@deakin.edu.au.
Stella O'ConnellInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, 3220 Geelong, Australia. stella.oconnell@deakin.edu.au.ORCID 0000-0003-4611-4065
Caryl A NowsonInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, 3220 Geelong, Australia. caryl.nowson@deakin.edu.au.ORCID 0000-0001-6586-7965
Robin M DalyInstitute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, 3220 Geelong, Australia. robin.daly@deakin.edu.au.
Deakin University · AUFlorey Institute of Neuroscience and Mental Health · AU

Funding

Agilent Technologies NAMeat and Livestock Australia NA
6 · The paper itself

Abstract

Selenium was suggested to play a role in modulating cognitive performance and dementia risk. Thus, this study aimed to investigate the association between selenium status and cognitive performance, as well as inflammatory and neurotrophic markers in healthy older adults. This cross-sectional study included 154 older adults (≥60 years) from Victoria, Australia. Participants were assessed for cognitive performance (Cogstate battery), dietary selenium intake (two 24-h food recalls), plasma selenium concentration, inflammatory markers (interleukin (IL)-6, -8, -10, tumor necrosis factor-alpha and adiponectin) and neurotrophic factors (brain-derived neurotrophic factor, vascular endothelial growth factor and insulin-like growth factor 1). Dietary selenium intake was adequate for 85% of all participants. The prevalence of selenium deficiency was low; only 8.4% did not have the minimum concentration in plasma required for optimization of iodothyronine 5' deiodinases activity. Multiple linear regression analysis revealed that plasma selenium was not associated with cognitive performance, inflammatory markers nor neurotrophic factors, independent of age, sex, body mass index (BMI), habitual physical activity,

Indexed as

CognitionCognitive DysfunctionNutritional StatusAdiponectinAgedBiomarkersBrain-Derived Neurotrophic FactorCross-Sectional StudiesCytokinesFemaleHumansInflammationInsulin-Like Growth Factor ILinear ModelsMalePrevalenceAdiponectinADIPOQ protein, humanBiomarkersBrain-Derived Neurotrophic FactorCytokinesIGF1 protein, humanInsulin-Like Growth Factor ISeleniumVascular Endothelial Growth Factor Acognitiondementiainflammatory markersneurotrophic factorsselenium

Identifiers

PMID30513714
PMCPMC6315874
OpenAlexW2902902546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.