Evidence map›Paper›PMID 30513611›Full record

ArticleMarine drugs2018

A Soft Coral-Derived Compound, 11-Dehydrosinulariolide, Induces G2/M Cell Cycle Arrest and Apoptosis in Small Cell Lung Cancer.

Yu-Chao Lin, Jui-Hsin Su, Shih-Chao Lin, Chia-Che Chang, Te-Chun Hsia, Yu-Tang Tung, Chi-Chien Lin

Abstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Analysis of Cembrane-Type Diterpenoids from Cultured Soft CoralInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. A novel biflavone fromFrontiers in pharmacology · 2022
    Article
  7. [Cell Cycle Checkpoint Kinase and Drug Resistance of Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2021
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu-Chao LinGraduate Institute of Clinical Medical Science, China Medical University, Taichung 404, Taiwan. D10001@mail.cmuh.org.tw.
Jui-Hsin SuNational Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan. x2219@nmmba.gov.tw.
Shih-Chao LinNational Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA 20110, USA. slin20@gmu.edu.ORCID 0000-0003-2942-5937
Chia-Che ChangInstitute of Biomedical Science, National Chung-Hsing University, Taichung 40227, Taiwan. chia_che@dragon.nchu.edu.tw.
Te-Chun HsiaDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung 404, Taiwan. derrick.hsia@msa.hinet.net.
Yu-Tang TungGraduate Institute of Metabolism and Obesity Sciences, Taipei Medical University, Taipei 110, Taiwan. f91625059@tmu.edu.tw.ORCID 0000-0002-4780-6496
Chi-Chien LinGraduate Institute of Clinical Medical Science, China Medical University, Taichung 404, Taiwan. lincc@dragon.nchu.edu.tw.ORCID 0000-0002-1464-0231

Funding

Ministry of Education iEGG and Animal Biotechnology Center from The Feature Areas Research Center Program within the framework of the Higher Education Sprout Project
6 · The paper itself

Abstract

11-Dehydrosinulariolide, an active compound that is isolated from the cultured soft coral

Indexed as

AnimalsAnthozoaAntineoplastic AgentsApoptosisCell Line, TumorCell ProliferationDisease ProgressionDiterpenesFemaleG2 Phase Cell Cycle CheckpointsHumansInjections, IntraperitonealLung NeoplasmsMiceMice, Inbred BALB CMice, Nude11-dehydrosinulariolideAntineoplastic AgentsDiterpenes11-dehydrosinulariolideapoptosiscell cycle arrestsmall cell lung cancersoft coral

Identifiers

PMID30513611
PMCPMC6315988

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.