Evidence map›Paper›PMID 30513602›Full record

ReviewDiagnostics (Basel, Switzerland)2018

Imaging as a Personalized Biomarker for Prostate Cancer Risk Stratification.

Kyle H Gennaro, Kristin K Porter, Jennifer B Gordetsky, Samuel J Galgano, Soroush Rais-Bahrami

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kyle H GennaroDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. kgennaro@uabmc.edu.
Kristin K PorterDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. kkporter@uabmc.edu.ORCID 0000-0001-9799-6913
Jennifer B GordetskyDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. jgordetsky@uabmc.edu.
Samuel J GalganoDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. samuelgalgano@uabmc.edu.
Soroush Rais-BahramiDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. sraisbahrami@uabmc.edu.ORCID 0000-0001-9466-9925
University of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomarkers provide objective data to guide clinicians in disease management. Prostate-specific antigen serves as a biomarker for screening of prostate cancer but has come under scrutiny for detection of clinically indolent disease. Multiple imaging techniques demonstrate promising results for diagnosing, staging, and determining definitive management of prostate cancer. One such modality, multiparametric magnetic resonance imaging (mpMRI), detects more clinically significant disease while missing lower volume and clinically insignificant disease. It also provides valuable information regarding tumor characteristics such as location and extraprostatic extension to guide surgical planning. Information from mpMRI may also help patients avoid unnecessary biopsies in the future. It can also be incorporated into targeted biopsies as well as following patients on active surveillance. Other novel techniques have also been developed to detect metastatic disease with advantages over traditional computer tomography and magnetic resonance imaging, which primarily rely on defined size criteria. These new techniques take advantage of underlying biological changes in prostate cancer tissue to identify metastatic disease. The purpose of this review is to present literature on imaging as a personalized biomarker for prostate cancer risk stratification.

Indexed as

active surveillancecancer stagingGleason scoremagnetic resonance imaging (MRI)radiation therapyradical prostatectomy

Identifiers

PMID30513602
PMCPMC6316045
OpenAlexW2902487399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.