Evidence map›Paper›PMID 30513477›Full record

ArticleDrug and alcohol dependence2019

Prevalence and patterns of opioid misuse and opioid use disorder among primary care patients who use tobacco.

William S John, He Zhu, Paolo Mannelli, Geetha A Subramaniam, Robert P Schwartz, Jennifer McNeely, Li-Tzy Wu

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Are you thinking what I'm thinking? Defining what we mean by "polysubstance use."The American journal of drug and alcohol abuse · 2024
    Article
  7. Article
  8. Review
  9. The Association of Opioid Use Disorder and COVID-19, a Longitudinal Study.International journal of preventive medicine · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

William S JohnDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA. Electronic address: william.john@duke.edu.
He ZhuDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Paolo MannelliDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
Geetha A SubramaniamNational Institute on Drug Abuse, Bethesda, MD, USA.
Robert P SchwartzFriends Research Institute, Inc., Baltimore, MD, USA.
Jennifer McNeelyDepartment of Population Health, New York University School of Medicine, New York, NY, USA.
Li-Tzy WuDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA; Department of Medicine, Division of General Internal Medicine, Duke University Medical Center, Durham, NC, USA; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA; Center for Child and Family Policy, Sanford School of Public Policy, Duke University, Durham, NC, USA. Electronic address: litzy.wu@duke.edu.
Duke Medical Center · USDuke University · USFriends Research Institute · USNational Institute on Drug Abuse · USNew York University · US

Funding

Project-003UG1DA013035 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Aimee N Campbell, Jennifer McNeely · 2015 to 2026
$130.3M
Southern Consortium Node of the Clinical Trials NetworkU10DA013727 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2000 to 2015
$34.4M
Clinical Trials Network: Mid-Atlantic Integrated Care Research CollaborativeUG1DA013034 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SCHWARTZ, ROBERT P, STITZER, MAXINE L · 2015 to 2019
$11.0M
Project-003UG1DA040317 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2015 to 2019
$9.0M
Substance Abuse & Treatment Gaps in Asians, Pacific Islanders & Multiple-race IndR01MD007658 · NIMHD · DUKE UNIVERSITY · PI WU, LI-TZY · 2013 to 2017
$1.8M
NIDA NIH HHS U10 DA013727NIDA NIH HHS UG1 DA013034NIDA NIH HHS UG1 DA013035NIDA NIH HHS UG1 DA040317NIMHD NIH HHS R01 MD007658
6 · The paper itself

Abstract

backgroundCurrent data suggest that opioid misuse or opioid use disorder (OUD) may be over represented among tobacco users. However, this association remains understudied in primary care settings. A better understanding of the extent of heterogeneity in opioid misuse among primary care patients who use tobacco may have implications for improved primary care-based screening, prevention, and intervention approaches.

methodsData were derived from a sample of 2000 adult (aged ≥18) primary care patients across 5 distinct clinics. Among past-year tobacco users (n = 882), we assessed the prevalence of opioid misuse and OUD by sociodemographic characteristics and past-year polysubstance use. Latent class analysis (LCA) was used to identify heterogeneous subgroups of tobacco users according to past-year polysubstance use patterns. Multinomial logistic regression was used to examine variables associated with LCA-defined class membership.

resultsPast-year tobacco use was reported by >84% of participants who reported past-year opioid misuse or OUD. Among those reporting past-year tobacco use, the prevalence of past-year opioid misuse and OUD was 14.0% and 9.5%, respectively. The prevalence of opioid misuse or OUD was highest among tobacco users who were male or unemployed. Three LCA-defined classes among tobacco users were identified including a tobacco-minimal drug use group (78.0%), a tobacco-cannabis use group (10.1%), and a tobacco-opioid/polydrug use group (11.9%). Class membership differed by sociodemographic characteristics.

conclusionsResults from this study support the benefit of more comprehensive assessment of and/or monitoring for opioid misuse among primary care patients who use tobacco, particularly for those who are male, unemployed, or polydrug users.

Indexed as

AdolescentAdultFemaleHumansMaleMarijuana SmokingMiddle AgedOpioid-Related DisordersPrevalencePrimary Health CareTobacco UseYoung AdultLatent class analysisOpioid use disorderPolysubstancePrimary careTobacco use

Identifiers

PMID30513477
PMCPMC6329633
OpenAlexW2902323183

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.