Evidence map›Paper›PMID 30513054›Full record

ArticleRNA biology2018

Bovine leukemia virus pre-miRNA genes' polymorphism.

I M Zyrianova, S N Koval'chuk

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. BLV-miR-B1-5p PromotesAnimals : an open access journal from MDPI · 2023
    Article
  2. Article
  3. Article
  4. Bovine leukemia virusVirulence · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

I M Zyrianovaa Federal State Budget Scientific Institution Center of Experimental Embryology and Reproductive Biotechnologies , Moscow , Russian Federation.ORCID 0000-0003-1871-8750
S N Koval'chuka Federal State Budget Scientific Institution Center of Experimental Embryology and Reproductive Biotechnologies , Moscow , Russian Federation.ORCID 0000-0002-5029-0750

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs with a wide distribution in nature among the living things. They play a key role both in normal signaling pathways and in pathological ones. Bovine leukemia virus (BLV) is an oncogenic retrovirus of Deltaretrovirus genus causing persistent infection in its natural hosts - cattle, zebu and water buffalo with diverse clinical manifestations through the defeat of B-lymphocytes (B-cells). Ten BLV encoded miRNAs (further miRs-B) transcribed from five different pre-miRNA (further pre-miR-B) genes are abundantly detected in BLV infected B-cells. Here we report about several alleles of each of pre-miRs-B' genes, some of which have a highly significant association with an increase or a decrease of the number of leukocytes (WBCs - white blood cells) in BLV-infected cows.

Indexed as

Polymorphism, GeneticRNA, ViralAllelesAnalysis of VarianceAnimalsBiomarkersCattleLeukemia Virus, BovineMicroRNAsBiomarkersMicroRNAsRNA, ViralBLVgenemiRNApolymorfism

Identifiers

PMID30513054
PMCPMC6333434
OpenAlexW2903254025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.