Evidence map›Paper›PMID 30512024›Full record

ArticleChemical communications (Cambridge, England)2018

A symbiotic supramolecular approach to the design of novel amphiphiles with antibacterial properties against MSRA.

Stilyana N Tyuleva, Nyasha Allen, Lisa J White, Antigoni Pépés, Helena J Shepherd, Paul J Saines, Rebecca J Ellaby, Daniel P Mulvihill, Jennifer R Hiscock

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stilyana N TyulevaSchool of Physical Sciences, University of Kent, Canterbury, CT2 7NH, UK. J.R.Hiscock@Kent.ac.uk.
Nyasha Allen
Lisa J White
Antigoni Pépés
Helena J Shepherd
Paul J Saines
Rebecca J Ellaby
Daniel P Mulvihill
Jennifer R Hiscock

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we identify supramolecular self-associating amphiphiles (SSAs) as a novel class of antibacterials with activity towards methicillin-resistant Staphylococcus aureus. Structure-activity relationships have been identified in the solid, solution and gas phases. Finally, we show that when supplied in combination, SSAs exhibit increased antibacterial efficacy against these clinically relevant microbes.

Indexed as

AnthracenesAnti-Bacterial AgentsCrystallography, X-RayHydrogen BondingMethicillin-Resistant Staphylococcus aureusMicroscopy, FluorescenceMolecular ConformationQuaternary Ammonium CompoundsStructure-Activity RelationshipanthraceneAnthracenesAnti-Bacterial AgentsQuaternary Ammonium Compoundstetrabutylammonium

Identifiers

PMID30512024
PMCPMC6336146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.